Elite Journal of Public Health. Volume 2 issue 3(2024), Pp. 52-62 https://epjournals.com/journals/EJPH Citation: Obeagu EI, Obeagu GU. Culturally Tailored Education: A Key to Adolescent Sickle Cell Disease Prevention. Elite Journal of Public Health, 2024; 2 (3): 52-62 Culturally Tailored Education: A Key to Adolescent Sickle Cell Disease Prevention * Emmanuel Ifeanyi Obeagu 1 and Getrude Uzoma Obeagu 2 1 Department of Medical Laboratory Science, Kampala International University, Uganda 3 School of Nursing Science, Kampala International University, Uganda * Corresponding authour: Emmanuel Ifeanyi Obeagu, Department of Medical Laboratory Science, Kampala International University, Uganda, emmanuelobeagu@yahoo.com, ORCID: 0000-0002- 4538-0161 Abstract Sickle cell disease (SCD) is a genetic disorder affecting millions globally, particularly among adolescents in marginalized communities. Despite medical advancements, prevention remains a paramount strategy in managing SCD. Culturally tailored education emerges as a promising approach, addressing the unique needs of adolescents and their communities. This review explores the significance of culturally tailored education in adolescent SCD prevention, highlighting its role in enhancing awareness, promoting healthy behaviors, and fostering community engagement. We discuss strategies, challenges, and future directions for implementing culturally sensitive interventions to mitigate healthcare disparities and improve outcomes in adolescent SCD. Keywords: Culturally tailored education, adolescent health, sickle cell disease, prevention, community engagement, healthcare disparities Introduction Sickle cell disease (SCD) poses a significant global health challenge, particularly among adolescents in marginalized communities. With approximately 20 million individuals affected worldwide, SCD remains a pressing concern due to its chronic nature and associated complications. Adolescents, in particular, face unique challenges in managing this inherited blood disorder, including increased susceptibility to infections, acute pain crises, and long-term organ damage. Despite advancements in medical treatments, prevention remains paramount in reducing the burden of SCD-related morbidity and mortality among adolescents. Culturally tailored education emerges as a promising strategy to address the multifaceted needs of adolescents and