Citation: Idris, Z.; Zakaria, Z.; Yee, A.S.; Fitzrol, D.N.; Ismail, M.I.; Ghani, A.R.I.; Abdullah, J.M.; Hassan, M.H.; Suardi, N. Light and the Brain: A Clinical Case Depicting the Effects of Light on Brainwaves and Possible Presence of Plasma-like Brain Energy. Brain Sci. 2024, 14, 308. https:// doi.org/10.3390/brainsci14040308 Academic Editors: Evanthia Bernitsas, Allan Bieber and Jack Zhang Received: 14 January 2024 Revised: 28 February 2024 Accepted: 22 March 2024 Published: 25 March 2024 Copyright: © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). brain sciences Case Report Light and the Brain: A Clinical Case Depicting the Effects of Light on Brainwaves and Possible Presence of Plasma-like Brain Energy Zamzuri Idris 1,2,3, *, Zaitun Zakaria 1,2,3 , Ang Song Yee 1,2,3 , Diana Noma Fitzrol 1,2,3 , Muhammad Ihfaz Ismail 1,2,3 , Abdul Rahman Izaini Ghani 1,2,3 , Jafri Malin Abdullah 1,2,3 , Mohd Hasyizan Hassan 3,4 and Nursakinah Suardi 5 1 Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia; zaitunzakaria@usm.my (Z.Z.); happy_4428@hotmail.com (A.S.Y.); diana_noma@hotmail.com (D.N.F.); ihfazrose5919@usm.my (M.I.I.); yoppghani@gmail.com (A.R.I.G.); brainsciences@gmail.com (J.M.A.) 2 Brain and Behavior Cluster (BBC), School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia 3 Hospital Universiti Sains Malaysia (HUSM), Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia; hasyizan@usm.my 4 Department of Anesthesiology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia 5 School of Physics, Universiti Sains Malaysia, Gelugor 11800, Penang, Malaysia; nsakinahsuardi@usm.my * Correspondence: neuroscienceszamzuri@gmail.com; Tel.: +6-09-7676299; Fax: +6-09-7648613 Abstract: Light is an electromagnetic radiation that has visible and invisible wavelength spectrums. Visible light can only be detected by the eyes through the optic pathways. With the presence of the scalp, cranium, and meninges, the brain is seen as being protected from direct exposure to light. For that reason, the brain can be viewed as a black body lying inside a black box. In physics, a black body tends to be in thermal equilibrium with its environment and can tightly regulate its temperature via thermodynamic principles. Therefore, a healthy brain inside a black box should not be exposed to light. On the contrary, photobiomodulation, a form of light therapy for the brain, has been shown to have beneficial effects on some neurological conditions. The proposed underlying mechanisms are multiple. Herein, we present our intraoperative findings of rapid electrocorticographic brainwave changes when the brain was shone directly with different wavelengths of light during awake brain surgery. Our findings provide literature evidence for light’s ability to influence human brain energy and function. Our proposed mechanism for these rapid changes is the presence of plasma-like energy inside the brain, which causes fast brain activities that are akin to lightning strikes. Keywords: light; photobiomodulation; brainwaves; thermodynamics; quantum brain; plasma; black body; awake brain surgery; electrocorticography 1. Introduction Light is the opposite of darkness, and it is meaningful to followers of many religions across the world such as the festival of light (Diwali) for Hindus, the candle festival for Buddhists, and as a symbol of God and the first creation (metaphorical light or Nur in Arabic) for the Abrahamic religions. In the academic arena, light has been viewed as an electromagnetic force or energy or waves since the great Scottish mathematical physicist James Clerk Maxwell proved for the first time in history the unification of electric (with field) and magnetic (with vortex) forces. Scientists view electromagnetic light with its highest speed at approximately 300,000 km/s as fundamental to our health and life [1–5]. Our most important source of natural light is the sun. The sunlight or white light is in fact composed of visible and invisible light frequency spectrums. Visible light (which can be processed by our visual system) has wavelengths from about 380 nanometers (violet) to Brain Sci. 2024, 14, 308. https://doi.org/10.3390/brainsci14040308 https://www.mdpi.com/journal/brainsci