Open Journal of Urology, 2014, 4, 127-131 Published Online November 2014 in SciRes. http://www.scirp.org/journal/oju http://dx.doi.org/10.4236/oju.2014.411022 How to cite this paper: Kane, R., Niang, L., Diallo, Y., Jalloh, M., Ndiaye, A. and Gueye, S.M. (2014) Advanced Bladder Cancer in Senegal: Epidemiological and Clinical Aspects. Open Journal of Urology, 4, 127-131. http://dx.doi.org/10.4236/oju.2014.411022 Advanced Bladder Cancer in Senegal: Epidemiological and Clinical Aspects R. Kane 1* , L. Niang 2 , Y. Diallo 3 , M. Jalloh 2 , A. Ndiaye 1 , S. M. Gueye 2 1 Service urologie hôpital principal, Dakar, Senegal 2 Service urologie hôpital general de grand yoff, Dakar, Senegal 3 Service urologie, Thiés, Senegal Email: * donekane2008@yahoo.fr Received 29 August 2014; revised 18 September 2014; accepted 20 October 2014 Copyright © 2014 by authors and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/ Abstract Advanced bladder cancer remains particularly frequent in our practice. Aim: To evaluate the pro- portion of advanced bladder cancer at diagnosis and to describe the characterisitics at diagnosis. Materials and methods: We conducted a descriptive and retrospective study assessing 97 cases of advanced bladder cancer over a period of 10 years (January 2002 to January 2012) at the depart- ment of Urology of Hôpital Principal de Dakar and Hôpital Général de Grand Yoff. We included the records of all patients with a pathologic confirmation of locally advanced bladder cancer (T3, T4) and/or a visceral or lymph node metastasis. Results: Mean age was 47 years (Range: 25 - 80 years). The cohort comprised 69 men and 28 women with a sex ratio of 2.46. The reasons for referral were a hematuria (60.82%), pelvic mass (19.2%), irritative urinary symptoms (8.2%). Reported medical histories were: urinary schistosomiasis (13 patients), tobaccoo(10 patients), recurrent cystitis (8 patients). Indications of local extention were: inguinal lymph nodes (6 patients), tumoral hepatomegaly (5 patients), bone pain (15 patients). A cystoscopy was performed in 64.95% of patients in a mean time of 2.5 months. A Trans Urethral Resection of Bladder Tumour (TURBT) was performed in 77 patients with a mean time from referral of 4 months. Pathologic examination showed squamous cell carcinoma (42%), urothelial carcinoma (28%) and adenocarcinoma (9%). Thoraco-abdomino pelvic CT scan showed a loco regional extension in 18 patients, extension to the peri vesical fat in 3 patients and metastasis in 25 patients. Conclusion: Delayed diagnosis of bladder cancer is still common in Africa with a high mortality rate. A better management requires an improvement of the equipment in the hospital with an emphasis on the access to endoscopy allowing for an early diagnosis. Keywords Advanced Bladder Cancer, Schistosomiasis, Endoscopy * Corresponding author.