Penile Cancer: Report of 3 Cases and Review of the Literature Kouka SCN 1* , Diallo Y 1 , Seck F 1 , Diousse P 1 , Jalloh M 2 , Niang L 2 , Diop AK 3 , Diallo A 3 and Sylla C 1 1 Department of Urology, Faculty of Health Sciences, University of Thies, Senegal 2 Department of Urology, University Cheikh Anta Diop De Dakar, Senegal 3 Department of Surgery, County Hospital in Mbour, Senegal * Corresponding author: Saint Charles Nabab Kouka, Departement of Urology, Faculty of Health Sciences, University of Thies, Senegal, Tel: +221775525077; E-mail: saintkouka@yahoo.fr Recieved date: November 29, 2016; Accepted date: January 24, 2017; Published date: January 31, 2017 Copyright: © 2017 Kouka SCN, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Abstract Cancer of the penis is rare in Senegal. This rarity could be related to the preventive action of ritual circumcision that is widely practiced during childhood. We report 3 cases of penile cancer tumor. The average age of our patients was 42.5 years with as extreme 22 years and 67 years. The average time for consultation was 6 months. All patients were circumcised during childhood. Squamous cell carcinoma was found in 2 cases. The review of the literature shows the rarity of this tumor and the role of promoting factors: the absence of circumcision and papillomavirus infection Keywords: Penile cancer; Circumcision; Senegal Introduction Primary penile cancer is a rare neoplasm [1]. Its frequency varies in Western countries. It is estimated between 0.3% to 0.5% of human cancers in the USA [1] with an estimated incidence of less than 1 per 100,000 in Europe [1]. In Senegal, their primary penile cancer frequency is estimated at 0.35% of all cancers and 0.97% of urological cancers [2]. e most common histological form is squamous cell carcinoma (95%). [3] In Africa, there people view the issue as taboo and lack information, thus consultations occur at a late stage where the prognosis is guarded. e purpose of this study was to investigate the clinical and therapeutic aspects of neoplasms of the penis in our experience. Case Report Case 1 A 42 year old circumcised patient without other specific medical history, f presented with a painful wound in the penis lasting for two months without associated urinary disorders. e clinical examination of the penis showed friable, encrusted superficial ulceration of the glans, associated with induration of the corpus cavernosum to the proximal third of the penis (Figure 1). Inguinal lymph nodes and Troisier lymph nodes were not enlarged. Imaging results required for staging, which had included abdominal ultrasound, chest X-ray and a thoraco-abdominal pelvic CT scan, were normal. e patient was classified T2N0M0. Aſter discussion and consultation with a clinical psychologist physician, the patient agreed to surgical treatment. Amputation of two thirds (2/3) distal of the penis was achieved without inguinal lymph node dissection. Histopathological analysis a confirmed squamous cell carcinoma. e postoperative course was uneventful. No adjuvant therapy was administered postoperatively. e patient is alive aſter two years of postoperative follow-up. ere is no local or regional recurrence. e patient was unable to maintain normal sexuality with the penile stump. Figure 1: Squamous cell carcinoma. Case 2 A 67 year old illiterate, farmer married with six children, was seen in consultation for the management of painful and permanent swelling of the penis evolving for about 10 months. He was circumcised during childhood. On physical examination, the patient had an altered condition, a budding lesion, whitish interesting glans with a total induration of the corpus cavernosum down to the root of the penis and small, painless, mobile inguinal lymphadenopathy (Figure 2). Chest X- ray results revealed bilateral pulmonary opacities consistent with pulmonary metastasis. Histopathological analysis of the excisional biopsy of the lesion concluded a basoloide carcinoma of the penis, stage pT3 N2 Mx G1. e patient died on day 15 of hospitalization aſter a deep coma with no signs of neurological localization (Glasgow Score=4). Kouka et al., Med Sur Urol 2017, 6:1 DOI: 10.4172/2168-9857.1000182 Case Report Open Access Med Sur Urol, an open access journal ISSN:2168-9857 Volume 6 • Issue 1 • 1000182 M e d i c a l & S u r g i c a l U r o l o g y ISSN: 2168-9857 Medical & Surgical Urology