Accepted Manuscript Review CRISPR/Cas9 in insects: Applications, best practices and biosafety concerns Clauvis Nji Tizi Taning, Benigna Van Eynde, Na Yu, Sanyuan Ma, Guy Smagghe PII: S0022-1910(16)30313-4 DOI: http://dx.doi.org/10.1016/j.jinsphys.2017.01.007 Reference: IP 3597 To appear in: Journal of Insect Physiology Received Date: 20 September 2016 Revised Date: 28 November 2016 Accepted Date: 12 January 2017 Please cite this article as: Taning, C.N.T., Van Eynde, B., Yu, N., Ma, S., Smagghe, G., CRISPR/Cas9 in insects: Applications, best practices and biosafety concerns, Journal of Insect Physiology (2017), doi: http://dx.doi.org/ 10.1016/j.jinsphys.2017.01.007 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.