Open Journal of Rheumatology and Autoimmune Diseases, 2023, 13, 8-16 https://www.scirp.org/journal/ojra ISSN Online: 2164-005X ISSN Print: 2163-9914 DOI: 10.4236/ojra.2023.131002 Feb. 7, 2023 8 Open Journal of Rheumatology and Autoimmune Diseases Ankylosing Spondylitis in a West African Hospital Abdoulaye Barry 1 , Oumar Diouhé Bah 2 , Adama Bah 1 , Mamadou Lamine Diallo 1 , Kaba Condé 1 , Samba Frein Condé 1 , Aly Badra Kamissoko 1 1 Rheumatology Department of the National Ignace Deen Hospital in Conakry, Conakry, Guinea 2 Biomar 24 Medical Laboratory, Conakry, Guinea Abstract Introduction: Ankylosing spondylitis (AS) is an inflammatory rheumatic disease characterized by predominant axial and peripheral (enthesitis, sacroi- liitis) involvement affecting young subjects aged 30 to 40 years, 80% to 98% of cases are associated with HLA-B27. Objective: To determine the epidemio- logical profile of ankylosing spondylitis in the rheumatology department of the Ignace Deen National Hospital in Conakry (Guinea). Materials and Me- thods: This was a descriptive cross-sectional study carried out within the said department over a period of 18 months from July 1, 2018 to December 31, 2020, including all patients seen in consultation and/or hospitalized in the department in which the diagnosis of ankylosing spondylitis had been re- tained according to the modified New York criterion. The parameters studied were sociodemographic, clinical, paraclinical and therapeutic. Result: We collected 73 cases or 4.1% of ankylosing spondylitis out of a total of 1781 pa- tients seen during the study period. The male gender was represented with 54.8% for a sex ratio of 1.2 M/F. The average age of our patients was 32.18 ± 12.44 years with extremes ranging from 17 to 54 years. Axial involvement was present in 89.9% of cases with a lumbar predominance (95.2%), followed by the sacroiliac seat (35.5%), cervical (14.5%) and dorsal at 4.8%. The pain was chronic in 93.2% of cases. The most common drug treatment was taking anal- gesics and NSAIDs (100%) followed by cortisone infiltration (41.1%), corticos- teroids (30%), and physiotherapy (21.9%). Ankylosing spondylitis represents 83% of spondyloarthritis followed by undifferentiated spondyloarthritis (9.1%) and juvenile spondylitis (3.4%) were the most common conditions. Keywords Ankylosing Spondylitis, Rheumatology, Ignace Deen, Guinea How to cite this paper: Barry, A., Bah, O.D., Bah, A., Diallo, M.L., Condé, K., Condé, S.F. and Kamissoko, A.B. (2023) Ankylosing Spondylitis in a West African Hospital. Open Journal of Rheumatology and Autoimmune Diseases, 13, 8-16. https://doi.org/10.4236/ojra.2023.131002 Received: November 7, 2022 Accepted: February 4, 2023 Published: February 7, 2023 Copyright © 2023 by author(s) and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/ Open Access