1 1 Title: Increased maternal pregnancy complications in polycystic ovary syndrome appears to be independent of obesity- A systematic review, meta-analysis and meta- regression Mahnaz Bahri Khomami 1 B & M Midwifery; Anju E. Joham 1, 2 Ph.D.; Jacqueline A Boyle 1, 3 Ph.D.; Terhi Piltonen 4 Ph.D.; Michael Silagy 3 MBBS.; Chavy Arora 3 MBBS.; Marie L. Misso 1 MBBS; Helena J. Teede 1, 2, 5 Ph.D.; Lisa J. Moran 1 Ph.D. Affiliations: 1. Monash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia 3168 2. Diabetes and Vascular Medicine Unit, Monash Health, Melbourne, Victoria, Australia 3168 3. Department of Obstetrics and Gynaecology, Monash Health, Melbourne, Victoria, Australia 3168 4. Department of Obstetrics and Gynecology, PEDEGO Research Unit, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland 5. Monash Partners Academic Health Sciences Centre, Melbourne, Victoria, Australia 3181 Keywords: polycystic ovary syndrome, miscarriage, gestational diabetes mellitus, gestational hypertension, obesity, pregnancy Running title: Maternal pregnancy and delivery complications in PCOS Acknowledgment: A Monash International Postgraduate Research Scholarship supports M.B.K. An NHMRC Early Career Fellowship supports A.E.J. An NHMRC Career Development Fellowship supports J.A.B. The Sigrid Juselius Foundation, the Finnish Medical Foundation, the Academy of Finland supports T.P and H.J.T is supported by a fellowship from the National Health and Medical Research Council. A Future Leader Fellowship from the National Heart Foundation of Australia supports L.J.M. Page 1 of 43 Obesity Reviews