1 Obesity and Insulin Resistance: A Review of Molecular Interactions Running Title: Obesity and Diabetes Mellitus Habib Yaribeygi 1* , Mina Maleki 2 , Thozhukat Sathyapalan 3 , Tannaz Jamialahmadi 4,5 , Amirhossein Sahebkar 6,7,8* 1 Research Center of Physiology, Semnan University of Medical Sciences, Semnan, Iran 2 Chronic Kidney Disease Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran 3 Academic Diabetes, Endocrinology and Metabolism, Hull York Medical School, University of Hull 4 Halal Research Center of IRI, FDA, Tehran, Iran 5 Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 6 Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran 7 Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran 8 School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran *Corresponding Authors Amirhossein Sahebkar, Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad 9177948564, Iran. Tel: +985138002299; Fax: +985138002287; E-mail: sahebkara@mums.ac.ir; amir_saheb2000@yahoo.com Habib Yaribeygi, Research Center of Physiology, Semnan University of Medical Sciences, Semnan, Iran, Tel: +989355644190 The published manuscript is available at EurekaSelect via https://doi.org/10.2174/1566524020666200812221527