Journal of Basic & Applied Sciences, 2015, 11, 501-506 501
ISSN: 1814-8085 / E-ISSN: 1927-5129/15 © 2015 Lifescience Global
To Assess the Quality of Life in Patients Suffering from Allergic
Rhinitis
Nikhil Sharma
1
, Prithpal S. Matreja
2,*
, Monika Gupta
3
, Vipan Gupta
4
, Manish Gupta
5
and
Ashwani K. Gupta
2
1
MBBS Student, Final Year, Gian Sagar Medical College and Hospital, Village Ram Nagar, District Patiala,
Punjab, 140601, India
2
Associate Professor, Department of Pharmacology, Gian Sagar Medical College and Hospital, Village Ram
Nagar, District Patiala, Punjab, 140601, India
3
Associate Professor, Department of Obstetrics and Gynecology, Maharishi Markandeshwar Institute of
Medical Science and Research, Solan, Himachal Pradesh, 173229, India
4
Professor, Department of Otorhinolaryngology, Maharishi Markandeshwar Institute of Medical Science and
Research, Solan, Himachal Pradesh, 173229, India
5
Associate Professor, Department of Otorhinolaryngology, Gian Sagar Medical College and Hospital, Village
Ram Nagar, District Patiala, Punjab, 140601, India
Abstract: Background: Allergic Rhinitis (AR) associated with impairments in patients day-to-day functioning at home and
work is a global health problem. It’s associated with sleep disorders, emotional problems, impairment in activities, and
social functioning. However, it’s not known to what extent quality of life (QOL) scores, work impairment, or sleep is
altered in Indian setup hence, this study was designed to assess the quality of life of patients suffering from allergic
rhinitis.
Methodology: This prospective, observational, cross sectional study was conducted on patients suffering from allergic
rhinitis visiting the out patients department. The patients who gave written informed consent were divided into two groups
based on gender, Group 1 was males and Group 2 was females. A detailed history was taken and participants
underwent thorough medical examination, followed by assessment on Rhino conjunctivitis Quality of Life Questionnaire
(RQLQ) and WHOQOL – Bref scores.
Results: A total of 87 patients were screened of which 40 patients were enrolled in study. The average age of patients in
the study was 28.08±10.01, a total of 26 males and 14 females completed the study. There were significantly worse non
nose/eyes symptoms scores, practical problems, and emotional scores in patients in Group 2 as compared to Group 1.
Group 1 had better aspect of sleep, nasal symptoms, and eyes symptoms as compared to Group 2. Whereas, Group2
had better aspect of activities score as compared to Group 1.
Conclusion: To conclude both groups had compromised quality of life, with females being more affected as compared to
males
Keywords: Allergic rhinitis, quality of life, social, emotional, psychological.
INTRODUCTION
Allergic rhinitis (AR) is a major illness and disability
worldwide, emerging as a global health problem and
affects approximately 40 million people in the United
States of America (USA) [1, 2]. There has been an
increase in the overall prevalence of AR since the early
1980s across all age, sex, and racial groups and is
accounted as one of the most common chronic
diseases among all age groups in the USA [1, 3].
The symptoms of allergic rhinitis are mainly nasal
with complaints of rhinorrhea, nasal congestion, and
sneezing [2, 4]. The patients also tends to experience
*Address correspondence to this author at the Department of Pharmacology,
Gian Sagar Medical College and Hospital, Village Ram Nagar, Tehsil Rajpura,
District Patiala, Punjab, 140601, India; Mob: +91-9855001847;
Fax: +91-1762-520024; E-mail: drpsmatreja@yahoo.co.in
non-nasal symptoms which are troublesome, including
headache, thirst, and disturbed sleep with fatigue,
mood changes, depression, anxiety and impairments of
work, school performance, and cognitive function [2, 4].
Only 12.4% of patients consult a physician, and
instead choose to self-treat with home remedies and
over-the-counter (OTC) medications; although they
experience unpleasant symptoms with allergic rhinitis,
they do not seek medical advice and [5, 6]. Increases
in direct and in direct cost is associated with lack of
treatment, under treatment, or non adherence. The
direct, indirect, and hidden cost associated with allergic
rhinitis is expensive as well as debilitating [5].
Reinforcement is needed for patient education and for
physicians to implement existing evidence-based
guidelines for prevention and treatment [5]. The total
estimated cost of allergic rhinitis was between 1.2 and