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Journal of Pharmacognosy and Phytochemistry 2013; 2 (3): 45-49
ISSN 2278-4136
ISSN 2349-8234
JPP 2013; 2 (3): 45-49
© 2013 AkiNik Publications
Received: 18-7-2013
Accepted: 09-8-2013
Rashmi Tambe
Department of Pharmacognosy,
MCE Society’s Allana College of
Pharmacy, Azam Campus, Camp,
Pune, India.
Maushumi Kulkarni
Department of Pharmaceutics,
MCE Society’s Allana College of
Pharmacy, Azam Campus, Camp,
Pune, India.
Kiran Bhise
Department of Pharmaceutics,
MCE Society’s Allana College of
Pharmacy, Azam Campus, Camp,
Pune, India.
Correspondence:
Rashmi Tambe
Department of Pharmacognosy,
MCE Society’s Allana College of
Pharmacy, Azam Campus, Camp,
Pune, India.
E-Mail: rashmicloud9@rediffmail.com
Tel: +91-9922964713
Preliminary Phytochemical Screening and HPTLC
Fingerprinting of Bark Extracts of Symplocos racemosa
Rashmi Tambe, Maushumi Kulkarni, Kiran Bhise
ABSTRACT
Objective: To establish physical constants and fingerprint profile of Symplocos racemosa using
high performance thin layer chromatography (HPTLC) technique. Methods: Preliminary
phytochemical screening was done, physical constants were evaluated and HPTLC studies were
carried out. CAMAG HPTLC system equipped with Linomat V applicator, TLC scanner 3, Reprostar
3 and WIN CATS-4 software were used. Results: Preliminary phytochemical screening of the extract
showed the presence of alkaloids, triterpenes, tannins, saponins, glycosides, phenolic compounds and
flavonoids. The proximate analysis showed satisfactory result with respect to foreign matter, moisture
content, ash value and extractive values. HPTLC finger printing of methanol extract of bark powder
revealed presence of eight components 0.23 0.44, 0.57, 0.68 0.97,1.17,1.35,1.43 Component number
6 at Rf 1.17 showed maximum concentration.Aqueous extract of bark powder showed seven peaks
with Rf values in the range with their Rf value Rf - 0.23 0.27 0.32, 0.38 0.54, 0.75 Component
number 5 at 0.0.54 Rf showed maximum concentration. Conclusions: It can be concluded that
HPTLC fingerprint analysis of bark powder extract of Symplocos racemosa can be used as a
diagnostic tool for the correct identification of the plant and it is useful as a phytochemical marker
and also a good estimator of genetic variability in plant populations.
Keywords: Symplocos racemosa bark, Phytochemical Screening, Physical constants, HPTLC
Fingerprinting.
1. Introduction
The human being exploited to alleviate his suffering from injuries of deceases utilizing plant
growing around him. The plant kingdom still hold many species of plant containing substance
of medicinal value which have yet to be discovered and the large no. of plant are constantly
being screened for their possible pharmacological value in addition to already exploited plants
[1]
. As the results of modern isolation technique and pharmacological screening procedure, new
plant drugs usually find their way into modern medicines. Now a days maximum world
population depends on herbal medicines.
Medicinal plants often contain additional active principles other than the major active
principles and physiologically inert substances like cellulose and starch. As the constituents
derived from the medicinal plants proved the cure the medicinal plants proved to cure the
human disorders they isolated and used for their pharmacological action. The constituents
having particular therapeutic effect are identified and isolated
[2]
.
Standardization of plant materials is the need of the day. Several pharmacopoeia containing
monographs of the plant materials describe only the physicochemical parameters. Hence the
modern methods describing the identification and quantification of active constituents in the
plant material may be useful for proper standardization of herbals and its formulations
[3]
. Also,
the WHO has emphasized the need to ensure the quality of medicinal plant products using
modern controlled techniques and applying suitable standards
[4]
. Chromatographic
fingerprinting techniques are most significant methods which can be used for the routine herbal
drug analysis and for quality assurance. HPTLC offers better resolution and estimation of
active constituents can be done with reasonable accuracy in a shorter time
[5]
.