Jemds.com Original Research Article J Evolution Med Dent Sci / eISSN - 2278-4802, pISSN - 2278-4748 / Vol. 9 / Issue 36 / Sept. 07, 2020 Page 2636 Clinical Application of Fasting and Post-Prandial Lipid Profile in Patients of Chronic Kidney Disease Ajinkya Jamthe 1 , Anuj Varma 2 , Sandip Mohale 3 , Sourya Acharya 4 , Amol Andhale 5 , Akhilesh Annadatha 6 1 Department of Medicine, Datta Meghe Institute of Medical Sciences (Deemed to Be University), Sawangi Meghe, Wardha, Maharashtra, India. 2 Department of Medicine, Datta Meghe Institute of Medical Sciences (Deemed to Be University), Sawangi Meghe, Wardha, Maharashtra, India. 3 Department of Medicine, Datta Meghe Institute of Medical Sciences (Deemed to Be University), Sawangi Meghe, Wardha, Maharashtra, India. 4 Department of Medicine, Datta Meghe Institute of Medical Sciences (Deemed to Be University), Sawangi Meghe, Wardha, Maharashtra, India. 5 Department of Medicine, Datta Meghe Institute of Medical Sciences (Deemed to Be University), Sawangi Meghe, Wardha, Maharashtra, India. 6 Department of Medicine, Datta Meghe Institute of Medical Sciences (Deemed to Be University), Sawangi Meghe, Wardha, Maharashtra, India. ABSTRACT BACKGROUND Dyslipidemia is a traditional risk factor for cerebrovascular disease and cardiovascular disease (CVD). CKD is associated with dyslipidemia. Patients with CKD will be more prone to the CVD and cerebrovascular disease as compared to normal healthy individuals. Thus, it is important to cover the postprandial lipid profile for better assessment and treatment of dyslipidemia. We wanted to study the postprandial lipid profile in patients of CKD. METHODS This is a case control study conducted in Acharya Vinoba Bhave Rural Hospital (AVBRH) Sawangi (Meghe), Wardha, Maharashtra, between September 2016 and September 2018. In this study, we enrolled 150 cases and 75 controls. RESULTS Fasting lipid profile in CKD patients was higher as compared to controls and was found to have similar post-prandial lipid profile. When we compared the fasting and post-prandial lipid profile in patients with CKD, we found that a substantial difference existed. We found a considerable difference in the fasting and post-prandial lipid profiles even in the controls. CONCLUSIONS Patients with CKD and diabetes mellitus had a significant increase in the total cholesterol, triglycerides, low density lipoprotein and very low-density lipoprotein in the fasting and post-prandial state. In clinical practice, the implementation of standardized methodologies and biomarker profiles would allow for the early and reliable detection of those at risk. KEY WORDS CKD, Cholesterol, Dyslipidaemia, Triglycerides Corresponding Author: Dr. Anuj Varma. Associate Professor, Department of Medicine, Datta Meghe Institute of Medical Sciences (Deemed to Be University), Sawangi Meghe, Wardha, Maharashtra, India. E-mail: anujvarma1985@gmail.com DOI: 10.14260/jemds/2020/573 How to Cite This Article: Jamthe A, Varma A, Mohale S, et al. Clinical application of fasting and post-prandial lipid profile in patients of chronic kidney disease. J Evolution Med Dent Sci 2020;9(36):2636-2640, DOI: 10.14260/jemds/2020/573 Submission 01-05-2020, Peer Review 31-07-2020, Acceptance 07-08-2020, Published 07-09-2020. Copyright © 2020 JEMDS. This is an open access article distributed under Creative Commons Attribution License [Attribution 4.0 International (CC BY 4.0)]