Accepted Manuscript Deep convolutional neural network-based segmentation and classification of difficult to define metastatic spinal lesions in 3D CT data Jiri Chmelik, Roman Jakubicek, Petr Walek, Jiri Jan, Petr Ourednicek, Lukas Lambert, Elena Amadori, Giampaolo Gavelli PII: S1361-8415(18)30552-8 DOI: https://doi.org/10.1016/j.media.2018.07.008 Reference: MEDIMA 1394 To appear in: Medical Image Analysis Received date: 2 November 2017 Revised date: 6 July 2018 Accepted date: 30 July 2018 Please cite this article as: Jiri Chmelik, Roman Jakubicek, Petr Walek, Jiri Jan, Petr Ourednicek, Lukas Lambert, Elena Amadori, Giampaolo Gavelli, Deep convolutional neural network-based seg- mentation and classification of difficult to define metastatic spinal lesions in 3D CT data, Medical Image Analysis (2018), doi: https://doi.org/10.1016/j.media.2018.07.008 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.