1 Early and One-year Stroke Case Fatality in Sao Paulo, Brazil: Applying the WHO Stroke STEPS 1 2 Running head: Stroke Subtype Risk Factors and Case Fatality 3 4 Alessandra C. Goulart, MD PhD a-b , Isabela M. Bensenor a-c , MD, PhD, Tiotrefis G. Fernandes c,e , 5 PT, Airlane P Alencar PhD d , Ligia M Fedeli a , , Paulo A Lotufo, MD, Dr PH. a-b 6 7 8 9 a Hospital Universitário, University of São Paulo, São Paulo, Brazil 10 b Hospital das Clínicas, São Paulo, Brazil 11 c School of Medicine, University of São Paulo, São Paulo, Brazil 12 d Institute of Math and Statistics, University of São Paulo, São Paulo,Brazil 13 e . Federal University of Amazonas, Coari, Brazil. 14 15 16 Corresponding author 17 Alessandra C. Goulart 18 Hospital Universitário 19 Av. Lineu Prestes 256, Butantan – Cidade Universitária 20 CEP 05508-900 – São Paulo, SP - Brasil 21 Email: agoulart@hu.usp.br 22 Phone: 55-11-3091-9241 23 Fax: 55-11-30919241 24 25 Funding: This project was funded by Conselho Nacional de Pesquisa (CNPq) and Fundação de 26 Amparo a Pesquisa do Estado de São Paulo, São Paulo, Brazil. Drs. Bensenor and Lotufo are the 27 recipients of an established investigator award from CNPq, Brasilia, Brazil. Mr. Fernandes is the 28 recipient of a doctoral fellowship from CNPq, Brasilia, Brazil. 29 30 31 Words count: 2319 32 Abstract: 199 33