Research Article Antibiotic Susceptibility Patterns of ESβL Producers Isolated from the Mobile Phones Manjula NG , 1 Shilpa Borehalli Mayegowda, 1 L. Priyanka, 1 D. Priyanka, 1 Saad Alghamdi , 2 Shalini Choudary, 1 V. Sanchita, 1 G. Chishmitha, 1 Banan Atwah, 2 Zain Alhindi, 2 and Fahadul Islam 3 1 School of Basic and Applied Sciences, Dayananda Sagar University, Bengaluru, Karnataka, India 2 Laboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia 3 Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka 1207, Bangladesh Correspondence should be addressed to Manjula NG; manjulang-sbas@dsu.edu.in and Fahadul Islam; fahadul29-774@diu.edu.bd Received 1 April 2022; Accepted 13 May 2022; Published 27 May 2022 Academic Editor: Vijaya Anand Copyright © 2022 Manjula NG et al. is is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Mobile phones have become an indispensable part of human lives for communication, education, and entertainment activities. is study aims to evaluate the diversity pattern of bacterial contaminants on mobiles and to check antibiotic resistance profiles in 105 samples. e study revealed a contamination of 51% in men and 49% in women, the highest in the 21- to 30-year age group, evidencing the extreme use of mobiles by teenagers. e study observed Gram-negative bacteria (63%) versus Gram-positive bacteria (37%). Overall, Gram-negative bacterial isolates showed the highest sensitivity to antibiotic nitrofurantoin (90%) and the lowest in ampicillin (35%). Gram positive has highest incidence of sensitivity towards tigecycline (100%) and lowest in cefoxitin (20%). ESβL producers were found to be 21.0% and highest being in Klebsiella oxytoca (35%) followed by Klebsiella pneumonia (31%). Staphylococcus pseu- dintermedius and Staphylococcus capitis have been identified on the mobile phones for the very first time. Interestingly, some soil microbes were also isolated and unfortunately found to have some antibiotic resistance like Raoultella ornithinolytica and Sphingomonas paucimobilis. e results revealed that mobiles were contaminated with multidrug-resistant (MDR) pathogens, and this study also showed that few of the saprophytic soil strains have antibiotic resistance, which can be an alarming situation that needs to be addressed. 1. Introduction e mobile phone or smartphone have many attributes and characteristics that make it very attractive to both the young and the old. With the achievements in the field of technology, mobile phone, a portable electronic device for personal communication, has become an important part of one’s life, and its benefits have made it user friendly. However, the disadvantage of overlooking the health hazard has been a concern because many users do not take care of personal hygiene while using these phones. e extensive usage of mobile devices, such as the touch screen, renders the highest possible transmission fomites of several pathogens across various age groups. Furthermore, different users handle them constantly exposing and acts as a good carrier to an array of microorganisms [1,2]. ese mobile phones come in contact with many surfaces that are having germs during our daily activities. ese germs gradually start to accumulate on our mobile phones over a period of time. It has been observed that with the constant handling of the mobile generates heat that acts a primary source for the growth of microbes that are normally found on the skin. us, sanitising the phone and hands play an important role in our health system. Disease causing bacteria are thus able to get transferred from person to person through the direct contact and fomites [3]. In the current situation, there has been an incessant use and handling of mobile phones, and these devices have also been exposed to a variety of different pathogenic bacteria [4]. ese pathogens can survive on environmental surfaces, including mobiles and thus may perhaps act as a potential infectious source for humans. Mobiles tend to act as fomites for pathogenic microbes that are transmitted such as Hindawi Evidence-Based Complementary and Alternative Medicine Volume 2022, Article ID 1527488, 8 pages https://doi.org/10.1155/2022/1527488