*Author for correspondence Original Research Article MVP Journal of Medical Sciences, Vol 5(1), 87–91, January-June 2018 ISSN (Print) : 2348–263X ISSN (Online) : 2348-2648 DOI: 10.18311/mvpjms/2018/v5i1/20882 Maternal and Perinatal Outcome in Hypertensive Disorders of Pregnancy - A Retrospective Study Padmaja Joshi 1 , Manasi Kathaley 2* , Swapnali Borade 3 , Rucha Dashrathi 4 1 Assistant Professor, 2 Professor, Department of Obstetrics and Gynaecology, Dr. Vasantrao Pawar Medical College Hospital and Research Centre, Nashik – 422003, Maharashtra, India; drpadmajajoshi78@gmail.com, manasihk65@gmail.com 3,4 PG Resident, Department of Obstetrics and Gynaecology, Dr. Vasantrao Pawar Medical College Hospital and Research Centre, Nashik – 422003, Maharashtra, India; swapnalirb@gmail.com, ruchad4@gmail.com Keywords: Eclampsia, Hypertensive Disorder of Pregnancy, Pre-Eclampsia, Prematurity Abstract Background: It was a retrospective observational study to know demographic factors, maternal and perinatal outcome in patients of hypertensive disorders of pregnancy admitted in a medical college and tertiary health care center. Introduction: Hypertensive disorders of pregnancy are one of the important cause of maternal morbidity and mortality in India. Hypertensive Disorders of Pregnancy (HDP) account for nearly 18% of all maternal deaths worldwide. Delivery at early gestational age in patients of HDP is associated with high perinatal morbidity and mortality resulting from prematurity. Method: Total number of 120 cases of hypertensive disorders of pregnancy admitted in our hospital was included in the study after satisfying inclusion and exclusion criteria. We studied demographic factors as well as maternal and perinatal outcome. Results: Majority of the patients i.e. 40% were in the age group of 21-30 yrs. 61% of patients were primi gravida and 25% of patients were second gravida. Maximum number of patients had gestational age ≥ 32weeks at the time of delivery. 26.6% patients, 73.4% patient’s and 12.5% patients were diagnosed as gestational hypertension, preeclampsia and eclampsia respectively. There was high incidence of HELLP and eclampsia in 12.5% each, DIC in (5%), APH in (4.1%), renal complications in (3.3%) and CNS complication were seen in 0.8%. 67.5% patients were delivered by vaginal route, 32.50% patients required LSCS. Majority of patients i.e., 60% underwent preterm delivery, 34% delivered at term. Maternal mortality occurred in 8 patients (6.67%). HELLP and DIC were the leading causes of death. 70% patients had good perinatal outcome. There were 25.83% still births and 4.17% neonatal deaths. Conclusion: Hypertensive disorders of pregnancy are associated with increased maternal and perinatal morbidity and mortality. Good antenatal care, health education, early diagnosis, early referral to higher center and multidisciplinary approach will reduce morbidity and mortality in mother and baby. 1. Introduction Hypertension is one of the common medical complica- tions of pregnancy known to increase the risk of maternal and perinatal morbidity and mortality 1 . Hypertensive disorders of pregnancy include chronic hypertension, gestational hypertension, pre-eclampsia, eclampsia and chronic hypertension with superimposed pre-eclampsia. Pre-eclampsia is a multisystem disorder of unknown etiology characterized by development of hypertension to the extent of 140/90mmHg or more with significant proteinuria aſter the 20 th week of gestation in a previously normo tensive and non proteinuric women 2 . Gestational hypertension is characterized by BP140/90mmHg or more diagnosed for the first time in pregnancy without proteinuria 2,3 . Eclampsia is defined as onset of convulsions in a woman with pre-eclampsia that cannot be attributed to other cause 2,3 . BP more than 140/90mmHg before pregnancy or diagnosed before 20 weeks of gestation is