Available Online At: Https://Jazindia.Com 714 Journal of Advanced Zoology ISSN: 0253-7214 Volume 43 Issue 1 Year 2022 Page 714-723 Fluoride Toxicity In Domestic Animals Of Chandrapur District, Maharashtra, India Anjali Phaley 1 , Mangala Thakare 2, Varsha Dhurvey 3* 1, 2 Department of Zoology, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur - 440033, India. *Corresponding Author: Dr. Varsha Dhurvey 3 *Professor, Department of Zoology, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur - 440033, India. Email: varshadhurvey@yahoo.com Article History Received- 06-10-2022. Revised - 05-11-2022. Acceptance- 02-12-2022 CC License CC-BY-NC-SA 4.0 Abstract A cross-sectional survey was carried out to evaluate the hazardous effects of fluoride on domestic animals in the fluoride-polluted areas of Chandrapur district in Maharashtra, India. Domestic animals, including buffalos, cattle, and goats from seven villages in the Warora tehsil, were the subjects of the current study. The animals showed signs of dental fluorosis to varying degrees, with subsurface water fluoride levels ranging from 0.53 to 5 mg/L. The elevated fluoride concentration functions as a potential pollutant.1966 of the 5176 animals examined for dental fluorosis with varied degrees of the condition in the cattle (34.3%), buffalo (46.37%), and goats (42.69%), respectively. It was determined that the prevalence of dental fluorosis was extremely significant (P<0.05). Environmental toxins and contaminants that causes several metabolic problems and also influence blood hence to evaluate the effects of fluoride toxicity on haematological parameters the present study was conducted. High fluoride concentrations were found in serum samples from buffalo, cattle, and goats, in contrast to their respective controls. Haematological analyses of naturally fluoridated animals showed a significant decline in haemoglobin concentration, total erythrocyte count, packed cell volume and leukocyte count, all indicators of fluoride-induced anaemia. According to the differential leukocyte count, animals from fluoride-polluted areas had significantly greater lymphocyte percentages and lower neutrophil percentages than those from non-contaminated areas. There are significant differences between the mean values of haematological parameters in animals of fluoride polluted and nonpolluted localities. The current study's conclusions will undoubtedly aid in addressing potential operating procedures for health problems related to fluorosis in domestic animals in the study area. Keywords: Fluorosis, Domestic animals, Buffalo, Cattle, Goats, Haematological and Dental parameters