Prevalence of Voiding Dysfunction After Finger-Guided Prostate Needle Biopsy
in Nigerian Men
Adegun Patrick Temi
*
and Olaogun Julius Gbenga
Department of Surgery, College of Medicine, Ekiti State University, Ado-Ekiti, Nigeria
*
Corresponding author: Adegun Patrick Temi, Department of Surgery, College of Medicine, Ekiti State University, Ado-Ekiti, Nigeria, Tel: +2348142098952; E-mail:
leoadeguns@hotmail.com
Recieved date: April 01, 2017; Accepted date: April 22, 2017; Published date: April 29, 2017
Copyright: © 2017 Temi AP, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted
use, distribution, and reproduction in any medium, provided the original author and source are credited., M.D., M.S.
Abstract
Background: Prostate biopsy is the standard procedure to detect prostate cancer. Opinion is still divided if
voiding disorders are part of the major complications worthy of attention. We investigated the prevalence of Lower
Urinary Tract Symptoms [LUTS] in men that underwent Finger-Guided Prostate Needle Biopsy [FGPNB] in Nigeria.
Materials and Methods: The study included 79 patients that underwent transrectal FGPNB used in the diagnosis
of prostate cancer. The indications for the prostate biopsy were abnormal digital rectal examination and/or an
elevated total serum prostate specific antigen (PSA) level (≥ 10 ng/mL). The participants received prophylactic
infusion of 100 mls of 200 mg ciprofloxacin 30 minutes to one hour before the biopsy. Peri-anal nerve block through
local infiltration of lignocaine with adrenaline was used as anaesthesia.
Results: Age range was 42-98 years with mean age of 67.4 ± 11.2 years. Cancer detection rate was 67.1%.
Prevalence of moderate LUTS pre-biopsy was 36.7%; one week after biopsy was 40.5%. Prevalence of 51.9% and
53.2% was recorded a month and three months post biopsy respectively. Moderate severity of LUTS was most
prevalent in the first and third month post-biopsy.
Conclusion: There was a progressive worsening of moderate symptomatology post biopsy in Nigerian men who
had prostate biopsy.
Keywords: Biopsy; Finger-guided; Prevalence; Prostate; Voiding
disorders
Introduction
Trans-rectal prostate biopsy is still the standard urological
procedure for detecting prostate cancer [1]. e procedure is relatively
safe with few major complications [2,3]. While some have reported
that prostate biopsy does not affect lower urinary tract symptoms [4],
others have recorded a risk of short-term worsening of voiding
dysfunctions aſter TRUS biopsy [5-8].
In most developed countries, finger-guided prostate needle biopsy
[FGPNB] is still being practiced due to paucity of Trans-rectal
ultrasound [TRUS] facility. ere is little or no record of voiding
dysfunction aſter the procedure. It is important to determine the
voiding functions post biopsy.
is study was to investigate the development of Lower urinary tract
symptoms [LUTS] aſter prostate needle biopsy in Nigerian men. To the
best of our knowledge, this is the first study that reported the
prevalence of voiding dysfunction aſter prostate needle biopsy in this
country.
Materials and Methods
is is a prospective study of men who underwent prostate biopsy at
the urology clinic of Ekiti State University Teaching Hospital, Ado-
Ekiti, Nigeria.
e study was conducted between January and December, 2016.
Inclusion criteria
1. Patients who were not on urethral catheter.
2. Patients aged 50 years & above, with serum PSA>10 ng/ml which
was our practice in low risk patients for prostate biopsy.
3. Patients with suspicious digital rectal examination [DRE] with
any level of PSA (All DREs were done with empty bladder).
4. Patients who have not undergone prostate biopsy in the last four
weeks.
Exclusion criteria
1. Patients who have Parkinson’s disease, stroke, encephalitis, or
temporal lobe epilepsy.
2. Patients who have brain tumors, dementias, Alzheimer’s disease,
Shy-Drager syndrome, and head injury.
3. Patients with a spinal cord injury especially, those with complete
lower cord lesions plus other disorders at the spinal level (e.g., spina
bifida, disc herniation, syringomyelia, tumor, transverse myelitis, and
multiple sclerosis).
4. Patients who did not give consent.
Temi et al., Med Sur Urol 2017, 6:2
DOI: 10.4172/2168-9857.1000184
Research Article Open Access
Med Sur Urol, an open access journal
ISSN:2168-9857
Volume 6 • Issue 2 • 1000184
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ISSN: 2168-9857
Medical & Surgical Urology