Potential of overpowering Drugs Resistance in MC F-7/Adr cells by regulation of apoptotic pathways using sorafenib incorporating chitosan conjugated folic acid nanoparticles: An Experimental Study Asmaa Hassan Beni-Suef University Ahmed Nabil ( drnabil_100@psas.bsu.edu.eg ) Beni-Suef University Islam S. Ali Delta University for Science and Technology Zeinab Reyd Beni-Suef University Osama M. Ahmed Beni-Suef University Ahmed A. G. El-Shahawy Beni-Suef University Research Article Keywords: breast cancer, Sorafenib, chitosan, tumor targeting, apoptosis, overcome multidrug resistance Posted Date: April 28th, 2023 DOI: https://doi.org/10.21203/rs.3.rs-2860117/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Additional Declarations: No competing interests reported.