https://doi.org/10.33805/2572-6978.150 Volume 5 Issue 1 | PDF 150 | Pages 7 Dental Research and Management Citation: Qanbar A, Abdulla AAM, Abutayyem H and El Din Mohamed SK. Comparative evaluation of the efficacy of silver diamine fluoride, sodium fluoride and GC tooth mousse plus and fluoride varnish as an antibacterial agent in childhood caries: As a literature review (2021) Dental Res Manag 5: 1-7. 1 Review Article ISSN: 2572-6978 Comparative Evaluation of the Efficacy of Silver Diamine Fluoride, Sodium Fluoride and GC Tooth Mousse Plus and Fluoride Varnish as an Antibacterial Agent in Childhood Caries: As a Literature Review Areej Qanbar 1 , Abdulaziz Abdulla Mufrrah Abdulla 1 , Huda Abutayyem 2 and Sally Kamal El Din Mohamed 3* Affiliation 1 RAK College of Dental Sciences, RAK Medical and Health Sciences University, United Arab Emirates 2 Orthodontic Department, RAK College of Dental Sciences, RAK Medical and Health Sciences University, United Arab Emirates 3 Orthodontic and Pediatric Dentistry Department, National Research Centre, Egypt * Corresponding author: Sally Kamal El Din Mohamed, Orthodontic and Pediatric Dentistry Department, National Research Centre, Egypt, E-mail: sallykamaleldin@yahoo.com Citation: Qanbar A, Abdulla AAM, Abutayyem H, and El Din Mohamed SK. Comparative evaluation of the efficacy of silver diamine fluoride, sodium fluoride and GC tooth mousse plus and fluoride varnish as an antibacterial agent in childhood caries: As a literature review (2021) Dental Res Manag 5: 1-7. Received: Dec 01, 2020 Accepted: Mar 03, 2021 Published: Mar 08, 2021 Copyright: © 2021 Qanbar A, et al., This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Abstract Background: In preventive dentistry, it is important for the need to prevent rather than to treat early childhood caries and to improve the types of fluoride and application to see if the comparative efficacy is sufficient or insufficient because every type can relieve and give comfort to patients. Aims: To compare the effect of Silver Diamine Fluoride (SDF), fluoride varnish, fluoride gel and GC tooth mousse plus on Streptococcus mutants bacterial load. To evaluate the effect on the types of fluoride on caries. To compare the effect of prevention’s of early childhood caries by using different types of fluoride. Searching the databases using the keywords: sodium diamine fluoride; GC tooth mousse; fluoride varnish; fluoride gel; early childhood caries; caries; varnish; prevention. Materials and methods: 2010-December 2018, databases which were searched: MEDLINE via Ovid, Web of science, Embase, Cochrane Library, LILACS, and Dental specialties: pediatrics, oral preventive. Foreigner languages, editorials, letter to the editor, experimental studies with animals and Short communications were excluded from this review. Results: 2 studies assessed un-clear and need further research of SDF. 5 studies assessed that 12% of SDF has no effect but 38% has an effect with dentin and enamel with black staining as a disadvantage. 1 study showed that SDF is safe and effective compared to fluoride varnish, 2 studies showed that tooth mousse is recommended for early child caries without mentioning SDF and 3 studies found that it decreases the growth of mutants and aids in the remineralization of both enamel and dentin structure. Conclusion: To sum up this study silver diamine fluoride is effective and safe to use for preventing childhood caries than silver fluoride, GC tooth mousse and fluoride varnish, which saves time with increase accuracy and patient satisfaction. Keywords: Silver diamine fluoride, Childhood caries, Prevention Abbreviations: SDF-Silver Diamine Fluoride, DMFS-Decayed, Missing or Filled Tooth Surfaces, CPP-ACP-Casein Phosphopeptide-Amorphous Calcium Phosphate Introduction Dental caries is one of the most common chronic illnesses in the whole world, affecting people across all age gatherings and nations [1]. Carious teeth can be both prevented and arrested by utilizing fluoride-based materials for example professional applied varnishes [2]. Dental caries is the most continuous childhood chronic disease worldwide [3]. Childhood caries the available quantity of one or more Decayed, Missing or Filled Tooth Surfaces (DMFS) in any primary tooth in a preschool-mature youngster has been associated by the American Dental Association as an important feature of public health issue [4]. ECC initiates with a white -spot lesion in the upper primary incisors along the margins of the gingiva. If the lesions progress, cavities can progress that will lead to destruction of the tooth. Children with experienced early childhood caries will lead to future destruction of primary and permanent teeth, In fact some of the children with caries are suffering from lack of eating, underweight because of the associated pain, which is also related to iron deficiency. In the coming years, a decrease in general caries indicators has been accounted for; in any case, an expansion in childhood caries has been