864 Annals of Medical Research DOI: 10.5455/annalsmedres.2019.09.580 2020;27(3):864-9 Original Article Clinicopathologic features of operated gastric cancer patients, single center nine years experience Orhan Uzun 1 , Aziz Serkan Senger 1 , Mursit Dincer 2 , Erdal Polat 1 , Mustafa Duman 1 , Kamuran Cumhur Deger 3 , Huseyin Cigiltepe 4 , Ebubekir Gundes 5 , Durmus Ali Cetin 6 , Ulas Aday 7 , Sinan Yol 8 1 Kartal Kosuyolu High Speciality and Training Hospital, Clinic of Gastroenterological Surgery, Istanbul, Turkey 2 Firat University, Faculty of Medicine, Department of General Surgery, Elazıg, Turkey 3 Bezm-i Alem Vakif University, Faculty of Medicine, Department of General Surgery, Istanbul, Turkey 4 Fatih Sultan Mehmet Training and Research Hospital, Clinic of Gastroenterological Surgery, Istanbul, Turkey 5 Gazi Yasargil Training and Research Hospital, Clinic of General Surgery, Diyarbakir, Turkey 6 Sanliurfa Training and Research Hospital, Clinic of General Surgery, Sanliurfa, Turkey 7 Elazig Training and Research Hospital, Clinic of General Surgery, Elazıg, Turkey 8 Privite VIA Medicalpark Hospital, Clinicof General Surgery, Istanbul, Turkey Copyright © 2020 by authors and Annals of Medical Research Publishing Inc. Abstract Aim: Gastric cancer is one of most common malignancies in the world. In developed countries including Europe and United States, despite the advanced technology, advanced stages of gastric cancer are still common with a poor survival. In this study, we aimed to describe clinicopathological characteristics and outcomes of gastric cancer in patients who were operated in our clinic. Material and Methods: We respectively evaluated a total of 200 patients who underwent gastrectomy, D2 lymph node dissection due to gastric cancer between November 2006 and December 2015. Data including clinicopathologic features, postoperative complications, overall survival and prognostic factors affecting prognosis were analyzed and statistical analysis was performed. Data including clinicopathologic features, postoperative complications, overal survival and prognostic factors affecting prognosis were analyzed and statistical analysis was performed. Results: Of the patients, 134 (67%) were males and 66 (33%) were females. The mean age was 61.36±11.92 (28-91) years. Tumor localization was frequently low (57%). The most common postoperative complication, regardless of the type of gastrectomy, was the surgical site infection. The major of the patients had Stage 3 disease. The median overall survival was 24.9 (0.07-116.3) months and overall survival was 43.7%. Conclusion: Except for early stage, the chance of curative treatment is low in gastric cancer. Early diagnosis and treatment can yield improved outcomes for this patient population. Therefore, it is important to develop national programs for early diagnosis and to develop experienced endoscopists Keywords: Gastric cancer; gastrectomy; survival Received: 03.10.2019 Accepted: 10.02.2020 Available online: 13.03.2020 Corresponding Author: Orhan Uzun, Kartal Kosuyolu High Speciality and Training Hospital, Clinic of Gastroenterological Surgery, Istanbul, Turkey E-mail: orhuzu@hotmail.com INTRODUCTION Gastric cancer is the fourth among the most common cancers worldwide and the second among the cancer- related causes of death. More than 75% of the cases occurred in less developed countries (1). The incidence of gastric cancer varies depending on the country, and it can even vary based on ethnicity and dietary habits within the same country. Japan and Korea have the highest rates of gastric carcinoma in the World(2). Helicobacter pylori infection, consumption of salty foods and N-nitroso compounds, low intake of fresh fruits and vegetables, smoking, obesity are some common risk factors for gastric cancers (2). It is seen 2 to 3 times more frequently in males than females, and it occurs frequently in the sixth decade of life (3). Gastric cancer incidence, metastasis rate and mortality are high, early diagnosis, resection rate and 5 year survival rate is low(4). Surgical treatment of gastric cancer in early stages offer the chance of cure ande 5-year survival rate is 90%(4). However, the diagnosis rate is low since there is no specific symptom in gastric cancer, therefore most patientes come advanced stages,so surgery often is missed(4). Thus, advanced gastric cancer treatment is multidisciplinary in the form of surgery, adjuvant- neoadjuvant chemoradiotherapy(Song et al., 2017). Current treatment of gastric cancer, except for the local