Cronicon OPEN ACCESS EC EMERGENCY MEDICINE AND CRITICAL CARE EC EMERGENCY MEDICINE AND CRITICAL CARE Mini Review A Note on Human Herpes Simplex Viruses Developing Venereal Diseases and Cancer in Human Mohammad Salim 1 *, Mohammad Shahid Masroor 2 , Vivek Kumar Yadav 3 and Shagufta Parween 4 1 Sanjay Gandhi Smriti Govt. Autonomous P.G. College, Sidhi, A.P.S. University, Rewa, Madhya Pradesh, India 2 People’s College of Dental Sciences and Research Center, People’s University, Bhopal, Madhya Pradesh, India 3 Department of Biotechnology, Kamla Memorial College, Sidhi, A.P.S. University, Rewa, Madhya Pradesh, India 4 Department of Human Anatomy, All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India Citation: Mohammad Salim., et al. “A Note on Human Herpes Simplex Viruses Developing Venereal Diseases and Cancer in Human”. EC Emergency Medicine and Critical Care 5.6 (2021): 75-78. *Corresponding Author: Mohammad Salim, Professor, Sanjay Gandhi Smriti Govt. Autonomous P.G. College, Sidhi, A.P.S. University, Rewa, Madhya Pradesh, India. Received: May 18, 2021; Published: May 25, 2021 Abstract The most commonly known to us as herpes viruses, the herpes simplex viruses (HSVs) are of two types i.e. HSV-1 and HSV-2. Herpes simplex viruses are usually transmitted via sharing objects, intimate skin to skin contact, kissing and sexual contact including oral and anal sex. While HSV-1 produces fever blister or cold sores around the mouth, HSV2 develops genital herpes in and around the genitals and rectum. As these viruses, sometimes, have also been reported to cause cancer in human, the present mini review deals with the study of etiology, transmission, diseases and cancer developing abilities of these viruses in human. Keywords: Human Herpes Simplex Viruses; Diseases and Cancer Abbreviations HHVs: Human Herpes Simplex Viruses; HSVs: Herpes Simplex Viruses; HSV-1: Herpes Simplex Virus-1; HSV-2: Herpes Simplex Virus-2; HSV-3: Herpes Simplex Virus-3; HSV-4: Herpes Simplex Virus-4; HSV-5: Herpes Simplex Virus-5; HSV-6: Herpes Simplex Virus-6; HSV-7: Herpes Simplex Virus-7; HSV-8: Herpes Simplex Virus-8; EBV: Epstein Bar Virus; CMV: Cytomegalovirus; KSHV: Kaposi’s Sarcoma Her- pesvirus Introduction Herpes viruses are popularly known to cause venereal diseases. They have been the most notorious, persistent, resistant, fast-growing and infectious microorganisms of human and animals. Indeed, every species of animal seems to have evolved with its own kind of herpes viruses. These viruses are now blamed to have caused more illnesses than any other human viruses [1]. All human herpesviruses (HHVs) known to us have been implicated in immune system evasion and suppression [2]. The human herpes viruses include herpes simplex viruses (HSV-1 and HSV-2), Varicella zoster virus (VZV or HHV-3), Epstein - Barr virus (EBV or HHV-4), Kaposi’s sarcoma-associated her- pesvirus (KSHV or HHV-8), cytomegalovirus (CMV or HHV-5) and roseoloviruses (HHV-6 and HHV-7) [3,4]. Human herpes simplex viruses are worldwide in occurrence. However, HSV-2 is more common in Sub-Saharan Africa. Though, these infections have never been lethal to us but can be annoying and painful. Since, in most of the cases, these infections are asymptomatic, they