Self-organized calix[4]arenes on Au110-1 Ã 2: A combined low-energy electron diffraction and scanning tunneling microscopy experimental study with molecular mechanics calculations Véronique Abad Langlais* and Yves Gauthier Laboratoire de Cristallographie, CNRS-BP166, 38042 Grenoble Cedex 9, France Hafid Belkhir Département de Physique, Université d’Annaba, 23000 Annaba, Algeria Olivier Maresca Unitat de Química Física, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain Received 17 February 2005; revised manuscript received 12 May 2005; published 18 August 2005 We report on self-assembly of calix4arenes deposited on Au110-1 2. The molecules consist of a macrocycle with four phenol rings linked by methylene groups in the ortho-position. The scanning tunneling microscopy images together with the low-energy electron diffraction patterns allow us to identify the molecular conformer and the unit cell. The intermolecular interactions are rather weak and are governed by stacking and van der Waals–type interactions as deduced from molecular mechanics calculations. The two-dimensional molecular self-ordering is due to a strong interaction with the gold substrate resulting in the replacement of the initial 1 2missing row reconstruction by a 1 3structure upon molecular adsorption. DOI: 10.1103/PhysRevB.72.085444 PACS numbers: 61.10.Nz, 05.65.b, 07.79.Cz, 02.70.c I. INTRODUCTION Organic molecules offer a large variety of complex mo- lecular architectures. When deposited on a metallic substrate, they provide functionality and high selectivity for applica- tions such as selective catalysis, sensors, lithography, and optoelectronics to name a few. 1–8 Moreover, organic mol- ecules have the capability to self-organize at surfaces in beautiful superstructures presenting long-range order. 9 In the last few years, concomitantly with the development of sur- face science techniques, they have attracted an increasing interest due to the possibilities they offer to perform selective two-dimensional 2Dsurface chemistry. The state of the art is fully described in a recent review that deals with large organic molecules. 10 To the large class of complex molecules considered therein, one has to add the whole family of calixnarenes where n =3–14 is the number of phenol groups that form the macrocycle size. The name, which de- rives from the Greek word for vase, was chosen because of the conformational vaselike shape. Usually, the synthesis of the calixarenes is based on phenol and formaldehyde con- densation under various conditions. 11 Moreover, additional complexity can be added since the aromatic cycles can be doted with different substituents, which permit us to design them for specific purposes. During the last decade, the calix- arenes have been extensively studied for their properties as receptors of neutral and ion guests. 12,13 Indeed, they play an important role in molecular recognition as hosts for smaller organic molecules, for ions, clusters or neutral guests. The main applications of calixarenes reported up to date are their use as sensors. 14,15 Functionalized calix4arene derivatives exhibit, for example, sodium ion selectivity while calix6arene has shown excellent sensitivity to cesium ions. Moreover, calixarenes embedded into polymeric membranes have been successfully used as ion-selective electrodes in electrolyte-insulator-semiconductor EISand ion-selective- field-effect-transistors ISFETstype sensors. Often, this kind of applications requires the elaboration of thin films. Such films could be obtained 1by self-assembly monolay- ers SAMswhen the calixarenes are functionalized by a -SH group, 16,17 2by sublimation of thick films as in the case of the p-tert-butyl-calix8arenes used as recognition agents in EIS and ISFETs sensors, 18–20 and 3by electrochemical deposition from solution, the most used deposition mode. Moreover, recent fundamental studies have revealed a coher- ent proton tunneling phenomenon in the cyclic network of four hydrogen bonds in calix4arenes. 21,22 In addition, previous works on calix4arenes and deriva- tives have revealed various adsorption modes on the dense Au111phase: the molecules may bind to the substrate via a lateral phenol group or via the lower rim of the four phenol groups. 23–25 The ability of these molecules to accept guest species and/or to act as a sensor will highly depend on their relative orientation and density and on their orientation rela- tive to the substrate. In this respect, the crystallographic ori- entation of the substrate is expected to play a crucial role. While Au111is nearly flat, the open Au110surface is highly corrugated with every other top row missing. Using this ridge-and-valley structure, we aim at producing molecu- lar arrangements at variance with those observed on Au111. Indeed, the top rows, which extend over hundreds if not thousands of Å, will possibly force the molecules to align, at least in one direction, and the inter-ridge distance, of the same order of magnitude as the long side of the molecules, may help obtaining higher molecular density. In the following, we show that the stablest conformer with “crown shape” yields a compact stacking and that the mol- ecules interacts so strongly with the substrate that the origi- nal 1 2missing row structure transforms into a 1 3 structure. This dense molecular layer is obtained at the price PHYSICAL REVIEW B 72, 085444 2005 1098-0121/2005/728/0854447/$23.00 ©2005 The American Physical Society 085444-1