Insomnia SLEEP VS. SHUTEYE LATENCY: PREVALENCE, PREDICTORS AND RELATION TO INSOMNIA SYMPTOMS IN A REPRESENTATIVE SAMPLE OF ADULTS L. Exelmans 1 , M. Gradisar 2 , J. Van den Bulck 3 . 1 KU Leuven, Leuven, Belgium; 2 Flinders University of South Australia, Adelaide, Australia; 3 University of Michigan, Ann Arbor, United States Introduction: An increasing number of people are going to bed without the intention to go to sleep. For them, bedtime has become a continuation of leisure. If so, commonly used measures of sleep have not been adjusted for this change in people's bedtime ritual, which may lead to inaccurate estimates of sleep onset latency (SOL) and the quantification of sleep-onset insomnia (SOL >30 min). We used the term shuteye latency (SEL) for time spent awake performing activities in bed before attempting to go to sleep (Exelmans & Van den Bulck, 2017). This study investigates (1) the prevalence, duration, and predictors of shuteye latency, (2) its association with insomnia symptoms (sleep quality and fatigue), and (3) the activities engaged in during shuteye latency. Materials and methods: A representative quota sample of 584 adults (18e96 years old, 51.2% women), stratified by gender, age, and educational level, participated in the study. Based on quota from recent census data, eligible participants were invited to participate in an online survey. We assessed chronotype with the Diurnal Type Scale (Torsvall & Akerstedt, 1980). We asked respondents how long they were awake in bed before deciding to go to sleep on weeknights (Sunday e Thursday) and weekend nights (Friday and Saturday). We asked how frequently they engaged in a list of activities in bed, categorized into non-screen activities, passive screen activities (television and computer) and interactive screen activities (smartphone, tablet, video- games). We used the Pittsburgh Sleep Quality Index (Buysse et al., 1989) and the Fatigue Assessment Scale (Michielsen et al., 2004). Results: One in five adults tried to sleep immediately at bedtime, 34.9% were awake for < 15 min, 27.6% between 15 and 30 min. Around 16% of respondents were awake for longer than 30 min on both week-and weekend nights, a cut-off score not dissimilar from sleep-onset insomnia (Lichtstein et al., 2003). Younger people and evening types reported longer shuteye latency. Longer shuteye latency corresponded with insomnia symptoms, i.e. poorer sleep quality (b ¼ .315, p< .001) and more fatigue (b ¼ .128, p< .001). Those with a shuteye latency longer than 30 min, were 6.96 (p< .001) times more likely to report poor sleep quality (PSQI >5) than those who tried to go to sleep immediately. This group also reported using both passive and interactive media more frequently than respondents with a shuteye latency below 30 min, but there was no difference between the groups for non-screen related activities. Conclusions: This study showed that going to bed and deciding to go to sleep are two separate decisions in most people. If both decisions occur at separate points in time, shuteye latency occurred e a new slice of 'me- time' right before lights out. This was associated with a progressive decline in sleep quality and increased fatigue. Shuteye latency may be yet another symptom of how sleep is increasingly under pressure from the modern lifestyle, but it may also reveal a previously undocumented symptom of insomnia. Restless Legs Syndrome (RLS) IS THERE RELATIONSHIP BETWEEN SEVERITY OF RLS AND IL-6 LEVELS? S. Fagundes , D. Fagundes. UNIFESP, S~ ao Paulo, Brazil Restless Legs Syndrome (RLS) is a sensorimotor disease that disturbs the sleep of 5 to 15% of population, and 12.95% of runners. Researches show us that exercises trigger interleukines (IL). IL-6 is more sensible among IL released after exercises. Another research shows that IL-6 raises more in RLS runners than in non RLS runners after running.When we see the number of runners increase each year, it raises the suspect: is there rela- tionship between severity RLS and IL-6 levels? Objective: Is there relationship between severity of RLS and IL-6 levels? Method: Sixty six nonprofessional athletes were investigated . The IRLSSG five questions about diagnosis of RLS and ten questions about severity of RLS were applied for researchers (SBRF, DJLF). IL-6 was analised in the basal time, after the marathon run and 72hrs after. Results: We found 10.60% of these athletes completed the requirement of RLS diagnosis. 57.14% of runners had mild-moderate RLS. 28.57% had se- vere-very severe RLS. The medium levels of IL-6 observed were: a) mild-moderate RLS group: basal : m¼ 3,585 (SD¼6.6097) , pos marathon : m¼100.95 (SD¼76.9757), after 72hrs :m¼19.8 (SD¼20.8505) (p0.05). b) Severe-very severe RLS: basal¼ m¼5,31 (SD¼64.2840), pos mara- thon : m¼188.81 (SD¼ 179.3788) and 72hrs: m¼36.815 (SD¼51.66829) (p0.05). Conclusion: Physical exercises stimulate IL-6 and return to basal levels after 72hrs. This mechanism is necessary to recover the metabolic and inflamatory environment control after endurance exercise. When this mechanism is broken, several diseases can appear, one of these is RLS.The dynamic of IL-6 seems like more compromised in severe RLS.The group was composed of marathon runners but only in severe group IL-6 was more elevated than in mild-moderate group. These results could suggest relationship between level of IL-6 and severity of RLS. Acknowledgements: The authors gratefully acknowledge the athletes for their patience as well Gianni M.S. dos Santos for help with statistic analysis. Restless Legs Syndrome (RLS) COULD ENDURANCE RESISTANCE EXERCISE PLAY A PROTECTIVE ROLE IN RLS? S. Fagundes , D. Fagundes. UNIFESP, S~ ao Paulo, Brazil Year after year the streets are awoke early on Sundays for the sound of thousand of sneakers trying to spend less time for each kilometer. Each one has one desire. Some run for health, others for diminish their time in the running, and anothers just for fun. Together with the run, it grows up the interest in study the sleep in these athletes. The research showed that 12.96% of runners have Restless Legs Syndrome (RLS). Objective: Could endurance resistance exercise play a protective role in RLS? Materials and methods: We study 66 nonprofessional runners. The re- searchers (SBRF and DJLF) applied a questionary about physical activity (run:( 5 , 10, 21 and 42 km), cycling , workout, swiming); how long; how many times for week). The questions were made using the International Restless Legs Syndrome Study Group(IRLSSG) five criteria diagnosis RLS; the severity of RLS was tested using: “severity questionary of IRLSSG”. How long he/she has RLS, how long run and if had RLS before began run. Interleukin 6 (IL-6) basal, after marathon and after 72hrs. Results: There were 66 nonprofessional runners. The age range 25 to 74 years old (medium 43.25 (DP 11.72).10.60 % has RLS. 42.86% has RLS before begin to run. 71.43% improves with run the symptoms and start to increase when stop running. Conclusion: The data show that RLS runners have higher levels of IL-6 than runners without RLS. And the resistance exercise stimulates IL-6. Besides these high levels, endurance exercise produce relief of symptom- atology and these athletes refer worst when they stop running. Probably there is a mechanism that envolves RLS and IL-6, and endurance resistance exercise plays a protective role in RLS. Acknowledgements: The authors gratefully acknowledge the athletes for their patience as well Gianni M.S. dos Santos for help with statistic analysis. Restless Legs Syndrome (RLS) PSYCHO-BEHAVIORAL PROFILE OF PARKINSON'S DISEASE PATIENTS WITH RESTLESS LEGS SYNDROME/WILLIS-EKBOM DISEASE A. Marques 1 , M. Figorilli 2 , B. Pereira 3 , P. Beudin 4 , T. Vidal 5 , F. Durif 6 , M.L. Fantini 7 . 1 Universitary Hospital CHU Clermont-Ferrand, Clermont-Ferrand, France; 2 University Clermont-Auvergne, Clermont-ferrand, France; 3 DRCI, CHU Clermont-Ferrand, France; 4 EEG and Sleep Unit, Neurology Dept, CHU Clermont-Ferrand, France; 5 CMRR- CHU Clermont-Ferrand, France; 6 Neurology, CHU Clermont-Ferrand/Universite Clermont Auvergne, Abstracts / Sleep Medicine 40 (2017) e3ee185 e92