BIOSCIENCES BIOTECHNOLOGY RESEARCH ASIA, September 2019. Vol. 16(3), p. 669-679 Published by Oriental Scientific Publishing Company © 2019 This is an Open Access article licensed under a Creative Commons license: Attribution 4.0 International (CC-BY). *Corresponding author E-mail: wafai47@hotmail.com Impact of Camel’s Milk on Aluminum Chloride (AlCl 3 ) Induced Toxicity in Rats Hala A. Abdolhaleem 1 , Magda Abd Elaziz 2 , Mostafa M. Bashandy 3 and Wafai Z. A. Mikhail 4 1 Dairy Department, Food Technology Research Institute, Agricultural Research Center, Minisrty of agriculture, Giza, Egypt. 2 Dairy Chemistry Department., Animal production Research Institute, Agricultural Research Center, Minisrty of agriculture,Dokki -Giza, Egypt. 3 Clinical pathology Department, Faculty of Veterinary Medicine, Cairo University,Giza,Egypt. 4 Department of Natural Resources, Faculty of African Postgraduate Studies, Cairo University, Giza Egypt. http://dx.doi.org/10.13005/bbra/2782 (Received: 07 August 2019; accepted: 27 September 2019) The present study was carried out to evaluate the efficiency of camel’s milk to ameliorate the toxicity of aluminum chloride AlCl 3 on some hematological parameters; hepatic,renal functions andlipids profile; as well ashistopathological alterations of some organs. Forty rats (8 / group) were divided into 5 treatment groups:Group1: Normal rats (negative control); Group2: AlCl 3 induced toxicity rats (positive control); Group3: AlCl 3 induced toxicity rats fed with raw camel milk; Group4: AlCl 3 induced toxicity rats fed with heat treated camel milk; andGroup5: AlCl 3 induced toxicity rats fed with sweet acidophilus camel milk. Rats were treatedby 5ml camel’s milk 10 min before the administration of 1 ml AlCl 3 (0.5 mg / kgbody weight); and had their respective doses daily for 30 successive days orally. AlCl 3 oral administration resulted in a significant decrease in red blood cells count (RBC’s), significant increase in mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH); while hemoglobin (Hb), hematocrite (Hct), platelets(plt), reticulocytes (Ret), mean corpuscular hemoglobin concentration (MCHC) did not revealed significant changes; the obtained anemia was macrocytic normochromic. The lipids profile; hepatic and renal functions showed non significant changes between different groups; however, histopathological examination showed variable alterations of varying severity in some organs; besides their response to camel’s milk administration. Camel’s milk administration in groups 3, 4, 5 alleviated the toxic effect of AlCl 3 with variable degrees between different groups. Keywords: Aluminum chloride, Camel’s milk, Kidney and liver functions, Lipids profile, Macrocytic normochromic anemia, Red blood cells. Aluminum (Al), the third most abundant element of the Earth’s crust, is found in combination with oxygen, silicon, fluorine and other elements in the soil, rocks, clays and gems; nonessential and toxic metal in humans 1 . With the industrialization and consequent pollution, Al is increasingly taken into our bodies through foods, air, water, and even drugs 2 .Food is the primary common sourceof Al; include yellow cheese, salt, herbs, spices, tea leaves, food additives 3 .The use of Al and its