age of the patients was 55.95 yrs, of which 89.58 % were males. The average weight was 72.67 kg. The indications for PCI were 46.18 % Unstable angina, 20.72% NSTEMI and 33.10% STEMI. 86.92% pa- tients took a loading dose of 60 mgs whereas 13.08% patients who had taken loading dose of clopidogrel were given only mainte- nance dose of 10 mgs/day. A total of 26 adverse events were noticed. Preliminary analysis revealed death of 2 patients due to possible stent thrombosis. Three patients required revasculari- zation (1 for stent thrombosis & 2 others for a different vessel intervention) and 1 required rehospitalisation however for a non cardiac cause. Major bleeding was seen in 1 patient whereas 19 patients experienced minor bleeds. Comparison of clopidogrel vs prasugrel in patients going for PCI-2 year follow-up K.A. Sambasivam, S. Natarajan, P.R. Vydianathan, Rajpal K. Abaichand, P.I.S. Chakravarthi, J.K. Periyaswamy, Bivin Wilson, S. Suvasini, M. Ramya G. Kuppuswamy Naidu Memorial Hospital, Coimbatore, India Background: There has been no Indian data on the efficacy and safety of prasugrel VS clopidogrel. Aim: To compare the efficacy and safety of prasugrel with that of clopidogrel in patients who underwent PCI. Methods: This is a retrospective observational study. We collected the data from patients who underwent elective/emergency PCI and were given prasugrel and clopidogrel. The study was between 2010- 2012. 235 patients formed the cohort. Group I consisted of 129 pa- tients who were treated with clopidogrel and group II was of 106 patients treated with clopidogrel. Prasugrel group received loading dose of (LD) 60 mg followed by maintenance dose (MD) of 10 mg once daily. LD and MD of clopidogrel was variable. We collected and analysed the baseline characteristics and in hospital , 30 days, 6 months, 18 months and 24 months major adverse vascular events. Primary end point was composite of death, ACS, stroke, emergency revascularisation, stent thrombosis, major bleeding. Individual secondary end points considered were admission for CCF, stent thrombosis, instent restenosis, minor bleed, hospital stay and ACS. Results: Mean age and sex distribution were similar in both the groups. Dyslipidemia, hypertension, family history, two vessel disease were higher in group II. More patients in group II had past history of MI, prior PCI and CABG .STEMI numbers were high in group I. Group I had significantly more primary PCI and use of GP IIB III a blocker . In hospital complications were comparable in both the groups. There was no significant difference between the groups in the composite primary end points during the entire follow up period. ACS was the only secondary endpoint that occurred significantly in group 2 (p 0.03). Conclusion: The efficacy and safety of prasugrel was comparable to that of clopidogrel in our study. Occurrence of ACS was significantly more in prasugrel group. Acute coronary syndrome in very young adults (<35 yrs) e Time to awake and act ! M. Selvaganesh, S.R. Veeramani, A.S. Arul, S. NainaMohammed, G.S. Sivakumar, S. Satheeshkumar, S. Selvaraju Government Rajaji Hospital, Madurai Medical College, Madurai, India Background: Acute Coronary syndrome in very young adults (<35yrs) was considered as an uncommon entity, recently shows rising incidence especially in India. ACS in this younger age is not, simply a problem of sufferers but a huge emotional and economical loss to the family. Materials and Methods: This is a prospective analytical study included patient <35yrs with ACS admitted in GovtRajajihospital (Madurai Medical College) in TamilNadu during Jan2013 to June 2014. Risk factors, clinical, angiographic profile and follow up data were recorded and analyzed. Results: Among the total 2180 patients with ACS, 5.8 % (n¼127) were very young adults. Youngest one was 11 yrs old with coro- nary anomaly. Mean age was 29.7yrs (±3.7) and only 8.6% (n¼10) were obese. Patients reached the hospital with median delay of 7hrs.Smoking (85%), male sex (93.9%) were the major conven- tional risk factors followed by low HDL (52%). Family history of premature coronary event seen in 12.9%, hyperhomocysteinemia, elevated Lpa and high fibrinogen were observed in 15%, 20% & 3.5% respectively. Anteriorwall MI with LAD occlusion was the commonest type (66.3%). Only 2 were undergone primary PCI (1.7%), 61% (n¼71) received thrombolytic therapy. Median delay for angiogram was 72hrs (3 days). Angiographically majority (53.4%) had SVD, 31% had recanalised vessels. Coronary anomaly was seen in 4 (3.4%) patients and pure ectasia in 3 (2.5%) patients. Mean EF was 42% (±7). In hospital mortality was 3.4% and 4.5 % (n¼5) during followup. Conclusion: Our observation showed, obstructive CAD in 56.9% of young ACS patients (<35yrs). This rapid progression of athero- sclerosis in Indians is not simply due to conventional risk factors alone but due to complex interaction of both conventional and novel risk factors. Significant admission and therapeutic delay implicate the need of active strategies to protect these budding adults. Study of factors associated with delayed thrombolysis and its impact on mortality and morbidity S.A. Punekar, A.R. Taksande, H.C. Shah, A.U. Mahajan, P.J. Nathani, Y.Y. Lokhandwala LTMG Hospital, Mumbai, India Background: Treatment delay in the management of STEMI / NSTEMI inversely correlates with prognosis and survival of the patients. This study was aimed to investigate factors associated with delay in the thrombolytic therapy of these patients in a municipal teaching hospital. Methods: Data was collected prospectively of all patients who were admitted with acute myocardial infarction from March 2014 e June 2014. Old myocardial infarction / old coronary artery bypass graft surgery/old percutaneous transluminal coronary angioplasty (PTCA) patients were excluded. The cardiology regis- trar in casualty initially filled the questionnaire and sent it to the cardiology registrar in ICCU. The cardiology registrar on duty in ICCU completed the questionnaire at discharge. The question- naire comprised of age, gender, weight, address, presenting symptoms, chest pain type, onset, events between chest pain onset and presentation to hospital, time between symptom onset and presentation to hospital, mode of transport to hospital, risk factors- smoking/diabetes/hypertension/dyslipidemia /family history , previous history of angina, socioeconomic status, indian heart journal 66 (2014) s1 es143 S18 brought to you by CORE View metadata, citation and similar papers at core.ac.uk provided by Elsevier - Publisher Connector