Vol.:(0123456789) 1 3
La radiologia medica
https://doi.org/10.1007/s11547-020-01259-y
RADIOTHERAPY
A technique for quantifying the sensitivity of dosimetric tool gamma
with 2D detector array in pretreatment IMRT plans by segment
deletion method
M. P. Arun Krishnan
1,2
· A. T. Bhagyalakshmi
1
· Raghavendra Holla
3
· Niyas Puzakkal
2
· C. P. Ranjith
2
· R. Vysakh
2
·
M. P. Irfad
2
· V. Ramasubramanian
1
· Jianping Hu
1
· M. Ummal Momeen
1
Received: 10 April 2020 / Accepted: 10 August 2020
© Italian Society of Medical Radiology 2020
Abstract
Objectives Motivation of this study is to check the sensitivity of dosimetric tool gamma with 2D detector array combina-
tion when unexpected errors occur while transferring intensity-modulated radiation therapy treatment plans from planning
system to treatment unit.
Methods This study consists of 17 head and neck cancer patient’s treatment plans. Nine types of verification plans are
created for all 17 clinically approved treatment plans by consecutively deleting different segments (up to eight) one by one
from each field of the plan. Decrement factor (χ) is introduced in our study which illustrated the degree of decay of gamma
passing rate when intentional errors are introduced. We analyzed the data by two different methods—one without selecting
the region of interest (ROI) in dose distributions and the other by selecting the region of interest.
Results By linear regression, the absolute value of slopes is 0.025, 0.024 and 0.015 without ROI and 0.030, 0.027 and 0.015
with ROI for 2%/2 mm, 3%/3 mm and 5%/5 mm criteria, respectively. The higher absolute value of the fitted slope indicates
the higher sensitivity of this method to identify erroneous plan in treatment unit. The threshold value for 2%/2 mm equivalent
to 95% passing criteria in 3%/3 mm used in clinical practice is obtained as 83.44%.
Conclusions The 2D detector array with dosimetric tool gamma is less sensitive in detecting errors when unprecedented
errors of segment deletion occur within the treatment plans.
Keywords IMRT · Pretreatment quality assurance · Decrement factor · Gamma · Error identification · Passing criterion ·
Region of interest
* Jianping Hu
jianpinghu@hotmail.com
* M. Ummal Momeen
ummalmomeen@gmail.com
M. P. Arun Krishnan
arunkrishnanmp@gmail.com
A. T. Bhagyalakshmi
bhagyalakshmiat@gmail.com
Raghavendra Holla
raghavendra.holla@gmail.com
Niyas Puzakkal
pniyas@gmail.com
C. P. Ranjith
ranjithcp007@gmail.com
R. Vysakh
vysakhraveendran92@gmail.com
M. P. Irfad
mpirfad@gmail.com
V. Ramasubramanian
vramasubramanian@vit.ac.in
1
School of Advanced Sciences, Vellore Institute
of Technology, Vellore 632014, India
2
MVR Cancer Centre and Research Institute,
Kozhikode 673601, India
3
Amrita Institute of Medical Sciences and Research Centre,
Kochi 682041, India