CASE REPORT Open Access
Spontaneous spinal epidural hematoma of
the thoracic spine after herbal medicine: a
case report
Eo Jin Kim
1
, Joonghyun Ahn
2
and Seung-Ju Kim
1*
Abstract
Background: Spontaneous spinal epidural hematoma (SSEH) is an uncommon disease, but it can lead to acute
cord compression with disabling consequences. Identifiable reasons for spontaneous hemorrhage are vascular
malformations and bleeding disorders. However, SSEH after taking herbal medicines has not been described yet.
Case presentation: A 60-year-old female experienced sudden back pain combined with numbness and weakness
in the lower limbs for several hours with no trauma, drug use, family history or any disease history. Her deep
tendon reflexes were normoactive, and Babinski was negative. An emergent MRI showed a spinal epidural
hematoma extending from T3 to T5. She was taken to surgery after immediate clinical and laboratory evaluations
had been completed. Emergency decompression with laminectomy was performed and the patient recovered
immediately after the surgery. Additional history taken from the patient at outpatient clinic after discharge revealed
that she had been continuously taking herbal medicine containing black garlic for 8 weeks.
Conclusion: To our knowledge, no report has been previously issued on SSEH after taking herbal medicines.
Although contradictory evidence is present on bleeding risks with herbal uses, we believe that it’s reasonable to
ascertain if patients with SSEP are taking herbal medication before or during spinal surgery.
Keywords: Spontaneous spinal epidural hematoma, Surgical treatment, Herbal medicines, Black garlic, Spinal cord
Background
Spinal epidural hematoma (SEH) is an idiopathic aggre-
gation of blood in epidural space which can be as acute,
chronic, spontaneously, post traumatic, or iatrogenic [1].
SEH occurring without a trauma is called as spontan-
eous SEH (SSEH) and it is an uncommon neurosurgical
emergency which can lead to acute cord compression
with disabling consequences [2]. The incidence of SSEH
was estimated to be 0.1 patients per 100,000 populations
per year [3]. As SSEH is one of the potentially reversible
pressure lesions on the spinal cord and roots, its prompt
diagnosis and treatment have a vital importance [1]. Al-
though some nonsurgical treatments have been reported
in cases that neurologic deficit improves in the early
phase of disease [1], early surgical decompression
(Laminectomy) is the first-line treatment modality for
SSEH [4, 5].
The etiology of SSEH remains unknown; however,
some predisposing factors have been reported, including
long term aspirin use as platelet aggregation inhibitor,
anticoagulant therapy for prosthetic cardiac valves,
therapeutic thrombolysis for acute myocardial infarction,
hemophilia, factor XI deficiency, vascular malformation,
Paget’s disease and pregnancy [6–8]. However, to the
best of our knowledge, no report has been previously is-
sued on SSEH after taking herbal medicines. Here, we
report a case of a 60-year-old woman who presented
with SSEH after taking herbal medicines and treated
successfully by surgical decompression.
Case presentation
A 60-year healthy female who was a hospital janitor of
our institute visited an emergency department with a
one-hour history of sudden low back pain with lower ex-
tremity motor and sensory deficit aggravated by bending.
* Correspondence: sju627@hotmail.com
1
Department of Orthopaedics, Hanil General Hospital, 308 Uicheon-ro,
Dobong-Gu, Seoul 132-703, South Korea
Full list of author information is available at the end of the article
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Kim et al. BMC Complementary and Alternative Medicine (2018) 18:291
https://doi.org/10.1186/s12906-018-2354-y