_____________________________________________________________________________________________________ *Corresponding author: E-mail: kiyesiadekemi@gmail.com; Journal of Advances in Medicine and Medical Research 32(11): 72-79, 2020; Article no.JAMMR.59148 ISSN: 2456-8899 (Past name: British Journal of Medicine and Medical Research, Past ISSN: 2231-0614, NLM ID: 101570965) Comparison of Serum Level of Bone Resorption Markers with Bone Densitometry in Elderly Individuals in Port Harcourt, Rivers State Kiyesi Adekemi 1* , Ehimen Phyllis Odum 2 and Victor Chukwuma Wakwe 2 1 Department of Chemical Pathology, Faculty of Basic Clinical Sciences, College of Medicine, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria. 2 Department of Chemical Pathology, Faculty of Basic Clinical Sciences, College of Health Sciences, University of Port Harcourt, Rivers State, Nigeria. Authors’ contributions This work was carried out in collaboration among all authors. Author KA designed the study, performed the statistical analysis, wrote the protocol and wrote the first draft of the manuscript. Authors EPO and VCW assisted in designing and supervising the work, made inputs in the manuscript and modification of the study. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JAMMR/2020/v32i1130535 Editor(s): (1) Dr. Anthony Olasinde, Federal Medical Centre Owo, Nigeria. Reviewers: (1) Deepti Gupta, India. (2) Hisaya Tanioka, Japan. Complete Peer review History: http://www.sdiarticle4.com/review-history/59148 Received 10 May 2020 Accepted 15 July 2020 Published 27 July 2020 ABSTRACT Introduction: This study concentrated on serum bone markers, N and C- telopeptide and tartrate resistant acid phosphatase (TRAP), and their concentrations were evaluated in the serum of elderly participants and compared with that of the young of the same gender. Markers for bone resorption are proteins, and they are mainly measured in the urine and serum, where they serve to assess bone turnover. Methodology: A cross-sectional prospective study conducted at the orthopaedic and Family Medicine Departments of the University of Port Harcourt Teaching Hospital, a public tertiary healthcare facility located in Choba and Alakahia communities of Obio/Akpor Local Government Areas of Rivers state, Nigeria, among elderly patients aged 60 years and above. Results: Considering the age of the test population, all the females were post-menopausal and no statistical difference was observed in relation to the results for gender in the study. Also, the Original Research Article