Case Report
Cavitating lung disease due to concomitant drug
resistant tuberculosis and invasive pulmonary
Aspergillosis in a post-partum patient: A case report
Animesh Ray
a
, J.C. Suri
b,*
, M.K. Sen
c
, S. Chakrabarti
c
, Ayush Gupta
a
,
Malini Capoor
d
a
Senior Resident, Department of Pulmonary, Critical Care & Sleep Medicine, Vardhman Mahavir Medical College, &
Safdarjang Hospital, New Delhi, India
b
Professor, Consultant Chest Physician & Head of Department, Department of Pulmonary, Critical Care & Sleep
Medicine, Vardhman Mahavir Medical College, & Safdarjang Hospital, New Delhi 110029, India
c
Associate Professor & Consultant Chest Physician, Department of Pulmonary, Critical Care & Sleep Medicine,
Vardhman Mahavir Medical College, & Safdarjang Hospital, New Delhi, India
d
Associate Professor & Senior Microbiologist, Department of Pulmonary, Critical Care & Sleep Medicine, Vardhman
Mahavir Medical College, & Safdarjang Hospital, New Delhi, India
article info
Article history:
Received 27 February 2014
Accepted 12 December 2014
Available online 12 March 2015
Keywords:
Invasive pulmonary aspergillosis
Drug resistant tuberculosis
Pregnancy associated tuberculosis
abstract
Many disorders can present as cavitating lesions in the lung. In this case report, a case of
mixed infection with drug resistant tuberculosis and invasive pulmonary aspergillosis in a
post-partum patient has been presented.
© 2015 Tuberculosis Association of India. Published by Elsevier B.V. All rights reserved.
1. Introduction
Cavitating lung lesions can arise due to various causes e both
infectious and non-infectious. In most of the cases meticulous
clinical examination and appropriate investigations can
pinpoint the cause. Rarely in some cases might more than one
cause be responsible. Pulmonary tuberculosis is a common
cause of cavitating lesions in our region. Fungal infections of
the lung due to Aspergillus species are well known. The prin-
cipal forms of pulmonary aspergillosis include colonizing
aspergillosis, invasive aspergillosis and allergic aspergillosis.
Aspergilloma with pulmonary tuberculosis usually occurs in
upper lobes in approximately 94% of cases.
1
Of the long term
sequelae of pulmonary tuberculosis, chronic pulmonary
aspergillosis is perhaps the most severe.
2
Clinical algorithms
to discriminate.
* Corresponding author. Tel.: þ91 011 26190958, þ91 9810097259.
E-mail address: docjcsuri@gmail.com (J.C. Suri).
Available online at www.sciencedirect.com
ScienceDirect
journal homepage: http://www.journals.elsevier.com/indian-
journal-of-tuberculosis/
indian journal of tuberculosis 62 (2015) 50 e53
http://dx.doi.org/10.1016/j.ijtb.2015.02.009
0019-5707/© 2015 Tuberculosis Association of India. Published by Elsevier B.V. All rights reserved.