_____________________________________________________________________________________________________ *Corresponding author: Email: magaji.buharii@gmail.com; Journal of Materials Science Research and Reviews 5(2): 26-32, 2020; Article no.JMSRR.56235 Synthesis, Characterization and Antibacterial Screening of Schiff Base and It’s Metal (II) Complexes Derived from 3-Aminophenol and Salicylaldehyde M. S. Mukhtar 1 , N. Y. Pindiga 1 , Buhari Magaji 1* , J. O. Nnamani 1 and M. M. Saddam 1 1 Department of Chemistry, Gombe State University, Nigeria. Authors’ contributions This work was carried out in collaboration among all authors. Authors NYP and BM designed, supervised and reviewed all the drafts of the manuscript. Authors MSM, JON and MMS carried out the research and wrote the first draft of the manuscript. All authors read and approved the final manuscript. Article Information Editor(s): (1) Dr. Anjanapura V. Raghu, Jain University, India. (2) Dr. Oscar Jaime Restrepo Baena, Universidad Nacional de Colombia, Colombia. (3) Dr. Yang Qu, Heilongjiang University, China. Reviewers: (1) Ioannis Gerothanassis, University of Ioannina, Greece. (2) Usmangani K. Chhalotiya, Gujarat Technological University, India. Complete Peer review History: http://www.sdiarticle4.com/review-history/56235 Received 23 February 2020 Accepted 29 April 2020 Published 07 May 2020 ABSTRACT New Schiff base ligand was synthesis via a condensation of the ligands in methanol. The Schiff base were synthesized in 1:2 molar ratio reactions. The complexes [Mn(HL 1 ) 2 Cl, Cu(HL 1 ) 2 and Ni(HL 1 ) 2 Cl] have been characterized on the basis of FTIR, electronic spectra, melting points/decomposition temperature, solubility and molar conductance. The in-vitro antibacterial activity of the complexes was tested using two gram-negative (Escherichia coli and Salmonella typhimurium) and two gram-positive (Staphylococcus pyogenes and Staphylococcus aureus) bacterial strains. The IR bands of Schiff bases showed a broad-band at 3317 cm -1 . The strong bands at 1590 cm -1 range was assigned to v(C=N) vibration which reveals coordination of the carbonyl group of the aldehyde and the amine group of the 3-aminophenol and salicylaldehyde Original Research Article