RESEARCH ARTICLE Nativity and Occupational Determinants of Physical Activity Participation Among Latinos Sandra E. Echeverría, PhD, 1 Anna Divney, DrPH, 2 Fatima Rodriguez, MD, MPH, 3 Madeline Sterling, MD, MPH, 4 Elizabeth Vasquez, DrPH, 5 Rosenda Murillo, PhD, 6 Lenny Lopez, MD, MPH 7,8 Introduction: Latinos in the U.S. bear a disproportionate burden of cardiovascular risk factors, including physical inactivity. Previous research among Latinos has focused on leisure-time physical activity, limiting understanding of the different ways in which populations, particularly working- class groups, achieve recommended levels of physical activity. This study examined associations of race/ethnicity; nativity; and leisure-time, transportation, and occupation-related physical activity among Latino and non-Latino white adults. Methods: Participants sampled in the 2007-2012 waves of the National Health and Nutrition Examination Survey self-reported domain-specific physical activity. Data were analyzed in 2016 -2017 using multivariable log binomial regression models to examine differences in meeting guide- lines for each physical activity domain separately and as total physical activity among Latinos (n=4,692) and non-Latino whites (n=7,788). Models were adjusted for sociodemographic character- istics and health status and tested interactions between nativity and occupational categories. Results: In adjusted models, foreign-born Latinos (prevalence ratio=0.70, 95% CI=0.63, 0.77) and U.S.-born Latinos (prevalence ratio=0.85, 95% CI=0.76, 0.95) were least likely to meet physical activity guidelines through occupation-related and leisure time physical activity, when compared with non-Latino whites. By contrast, foreign-born Latinos were more likely to meet physical activity guidelines through transportation physical activity than non-Latino whites (prevalence ratio=1.26, 95% CI=1.01, 1.56) and were proportionately more likely to participate in vigorous modes of physi- cal activity. Interaction results indicated that foreign-born Latinos were the least likely to meet physical activity guidelines compared with U.S.-born Latinos and non-Latino whites if they worked in non-manual occupational categories. All racial/ethnic groups working in manual occupations saw the largest increase (40%-50%) in meeting physical activity guidelines when occupation- related physical activity was combined with leisure-time and transportation physical activity. Conclusions: These findings suggest variability in the relationship between nativity and the physi- cal activity domain Latinos engage in compared with non-Latino whites, with occupation contrib- uting substantially to meeting physical activity recommendations for all population groups. Am J Prev Med 2018;000(000):1-9. © 2018 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved. From the 1 Department of Public Health Education, School of Health and Human Sciences, University of North Carolina at Greensboro, Greens- boro, North Carolina; 2 Department of Community Health and Social Sci- ences, CUNY Graduate School of Public Health and Health Policy, New York, New York; 3 Division of Cardiovascular Medicine and Cardiovascu- lar Institute, Stanford University, Stanford, California; 4 Department of Medicine, Weill Cornell Medical College, New York, New York; 5 Depart- ment of Epidemiology and Biostatistics, School of Public Health, Univer- sity at Albany, State University of New York, Rensselaer, New York; 6 Department of Psychological, Health, and Learning Sciences, University of Houston, Houston, Texas; 7 Department of Medicine, Division of Hospi- tal Medicine, University of California San Francisco, San Francisco, Cali- fornia; and 8 San Francisco VA Medical Center, San Francisco, California Address correspondence to: Sandra E. Echeverria, PhD, Department of Public Health Education, School of Health and Human Sciences, Univer- sity of North Carolina at Greensboro, 1408 Walker Avenue, Coleman Bldg-437, Greensboro NC 27402. E-mail: seecheve@uncg.edu. 0749-3797/$36.00 https://doi.org/10.1016/j.amepre.2018.07.036 © 2018 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved. Am J Prev Med 2018;000(000):1-9 1 ARTICLE IN PRESS