Int. J. Computational Science and Engineering, Vol. 8, No. 2, 2013 87 Copyright © 2013 Inderscience Enterprises Ltd. Intra-pixel multispectral processing of magnetic resonance brain images for tissue characterisation Clayton Chi-Chang Chen* Department of Radiology, Taichung Veterans General Hospital, No. 160, Sec. 3, Chung-Kang Rd., Taichung, 40705, Taiwan E-mail: ccc@vghtc.gov.tw *Corresponding author Englin Wong Remote Sensing Signal and Image Processing Laboratory, Department of Computer Science and Electrical Engineering, University of Maryland, Baltimore County, Baltimore, MD 21250, USA E-mail: lovemk6946@gmail.com Hsian-Min Chen Department of Biomedical Engineering, HungKuang University, No. 1018, Sec. 6, Taiwan Boulevard, Shalu District, Taichung, 43302, Taiwan E-mail: bme@web.hk.edu.tw Shih-Yu Chen Remote Sensing Signal and Image Processing Laboratory, Department of Computer Science and Electrical Engineering, University of Maryland, Baltimore County, Baltimore, MD 21250, USA E-mail: koberan3@gmail.com Jyh-Wen Chai Department of Radiology, Taichung Veterans General Hospital, No. 160, Sec. 3, Chung-Kang Rd., Taichung, 40705, Taiwan and Department of Radiology, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan E-mail: hubt@mail.vghtc.gov.tw Ching-Wen Yang Computer Center, Taichung Veterans General Hospital, No. 160, Sec. 3, Chung-Kang Rd., Taichung, 40705, Taiwan E-mail: cwyang@vghtc.gov.tw San-Kan Lee Department of Radiology, Taichung Veterans General Hospital, No. 160, Sec. 3, Chung-Kang Rd., Taichung, 40705, Taiwan E-mail: sklee@vghtc.gov.tw