Page 1/22 Ecacy of 5-hydroxytryptamine-3 (5-HT3) antagonists adjuvant therapy for moderate to severe obsessive–compulsive disorder: A systematic review and meta-analysis of randomized clinical trials Negin Eissazade Iran University of Medical Sciences Hesam Mosavari Iran University of Medical Sciences Shayan Eghdami Iran University of Medical Sciences Mahsa Boroon Psychosocial Health Research Institute (PHRI), Iran University of Medical Sciences Faria Ashra Institute for Cognitive Science Studies Mohammadreza Shalbafan ( Shalbafan.mr@iums.ac.ir ) Psychosocial Health Research Institute (PHRI), Iran University of Medical Sciences Article Keywords: Obsessive-Compulsive Disorder, Selective Serotonin Reuptake Inhibitors, Serotonin 5-HT3 Receptor Antagonists, Ondansetron, Granisetron, Tropisetron Posted Date: April 24th, 2023 DOI: https://doi.org/10.21203/rs.3.rs-2684590/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Additional Declarations: No competing interests reported. Version of Record: A version of this preprint was published at Scientic Reports on November 27th, 2023. See the published version at https://doi.org/10.1038/s41598-023-47931-x.