Obstet Gynecol Res 2021; 4 (4): 196-202 DOI: 10.26502/ogr068 Obstetrics and Gynecology Research - Vol. 4 No. 4 – December 2021. 196 Research Article Frequency and Risk Factors for Depression and Anxiety in Patients with Polycystic Ovary Syndrome Presenting in a Tertiary Care Hospital Karachi, Pakistan Amera Tariq 1* , Manahil Tariq Malik 2 , Humaira Tariq 3 , Samina Naseem Khattak 1 , Tehreem Yazdani 4 , Rameen Tariq Malik 5 , Shahzad Rauf 6 , Tariq Malik 7 1 Consultant Obstetrician and Gynaecologist, PNS Shifa Hospital, Karachi, Pakistan 2 Medical Student, Aga Khan University, Karachi, Pakistan 3 Consultant Obstetrician and Gynaecologist, Combined Military Hospital, Rawalpindi, Pakistan 4 Consultant Obstetrician and Gynaecologist, Military Hospital, Rawalpindi, Pakistan 5 Medical Student, Bahria University Medical and Dental College, Karachi, Pakistan 6 Consultant Psychiatrist, PNS Shifa Hospital, Karachi, Pakistan 7 Consultant Anaesthetist, PNS Shifa Hospital, Karachi, Pakistan * Corresponding Author: Amera Tariq, Consultant Obstetrician and Gynaecologist, PNS Shifa Hospital, Karachi, Pakistan Received: 18 September 2021; Accepted: 28 September 2021; Published: 05 October 2021 Citation: Amera Tariq, Manahil Tariq Malik, Humaira Tariq, Samina Naseem Khattak, Tehreem Yazdani, Rameen Tariq Malik, Shahzad Rauf, Tariq Malik. Frequency and Risk Factors for Depression and Anxiety in Patients with Polycystic Ovary Syndrome Presenting in a Tertiary Care Hospital Karachi, Pakistan. Obstetrics and Gynecology Research 4 (2021): 196-202. Abstract Objective: To determine the frequency and risk factors for depression and anxiety in patients with Poly cystic ovary syndrome (PCOS). Study design: Comparative Analytic Study. Setting and duration: Department of Obstetrics and Gynaecology at a tertiary care hospital in Karachi, Paki- stan from July 2020-December 2020. Materials and methods: All females with diagnosed PCOS aged between 15-45yrs were included in the study .A total of 270 females (n=135) formed the study group. Group A (n=135) constituted females diagnosed to have PCOS and group B (n=135) without PCOS.