MAGNETIC RESONANCE Compressed sensing MRI of different organs: ready for clinical daily practice? Bénédicte Marie Anne Delattre 1 & Sana Boudabbous 1 & Catrina Hansen 1 & Angeliki Neroladaki 1 & Anne-Lise Hachulla 1 & Maria Isabel Vargas 2 Received: 11 April 2019 /Revised: 28 May 2019 /Accepted: 11 June 2019 # European Society of Radiology 2019 Abstract Objectives The aim was to evaluate the image quality and sensitivity to artifacts of compressed sensing (CS) acceleration technique, applied to 3D or breath-hold sequences in different clinical applications from brain to knee. Methods CS with an acceleration from 30 to 60% and conventional MRI sequences were performed in 10 different applications in 107 patients, leading to 120 comparisons. Readers were blinded to the technique for quantitative (contrast-to-noise ratio or functional measurements for cardiac cine) and qualitative (image quality, artifacts, diagnostic findings, and preference) image analyses. Results No statistically significant difference in image quality or artifacts was found for each sequence except for the cardiac cine CS for one of both readers and for the wrist 3D proton density (PD)–weighted CS sequence which showed less motion artifacts due to the reduced acquisition time. The contrast-to-noise ratio was lower for the elbow CS sequence but not statistically different in all other applications. Diagnostic findings were similar between conventional and CS sequence for all the comparisons except for four cases where motion artifacts corrupted either the conventional or the CS sequence. Conclusions The evaluated CS sequences are ready to be used in clinical daily practice except for the elbow application which requires a lower acceleration. The CS factor should be tuned for each organ and sequence to obtain good image quality. It leads to 30% to 60% acceleration in the applications evaluated in this study which has a significant impact on clinical workflow. Key Points • Clinical implementation of compressed sensing (CS) reduced scan times of at least 30% with only minor penalty in image quality and no change in diagnostic findings. • The CS acceleration factor has to be tuned separately for each organ and sequence to guarantee similar image quality than conventional acquisition. • At least 30% and up to 60% acceleration is feasible in specific sequences in clinical routine. Keywords Magnetic resonance imaging . Acceleration . Image processing, computer-assisted . Data compression Abbreviations 3D Three-Dimensional BTFE Balanced turbo field echo Cine Cinematic sequence CNR Contrast-to-noise ratio CS Compressed sensing FFE Fast field echo FLAIR Fluid-attenuated inversion recovery FOV Field of view mDixon Multi-echo two-point Dixon MRCP Magnetic resonance cholangiopancreatography MSK Musculoskeletal PD Proton density SENSE Sensitivity encoding SPAIR Spectral attenuated inversion recovery Electronic supplementary material The online version of this article (https://doi.org/10.1007/s00330-019-06319-0) contains supplementary material, which is available to authorized users. * Bénédicte Marie Anne Delattre benedicte.delattre@hcuge.ch 1 Division of Radiology, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva 14, Switzerland 2 Division of Neuroradiology, Geneva University Hospitals , Geneva, Switzerland European Radiology https://doi.org/10.1007/s00330-019-06319-0