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International Journal of Mosquito Research 2022; 9(6): 107-115
ISSN: 2348-5906
CODEN: IJMRK2
IJMR 2022; 9(6): 107-115
© 2022 IJMR
www.dipterajournal.com
Received: 09-08-2022
Accepted: 11-09-2022
Narayan Lal Choudhary
Research Scholar
Wildlife Limnology and
Toxicology Research
Laboratory, Department of
Zoology, Government Meera
Girls College (MLSU), Udaipur,
Rajasthan, India
Pushkar Kumawat
Research Scholar
Wildlife Limnology and
Toxicology Research
Laboratory, Department of
Zoology, Government Meera
Girls College (MLSU), Udaipur,
Rajasthan, India
Pritesh Patel
Research Scholar
Wildlife Limnology and
Toxicology Research
Laboratory, Department of
Zoology, Government Meera
Girls College (MLSU), Udaipur,
Rajasthan, India
Nadim Chishty
Associate Professor, Department
of Zoology, Wildlife Limnology
and Toxicology Research
Laboratory, Government Meera
Girls College (MLSU), Udaipur,
Rajasthan, India
Corresponding Author:
Nadim Chishty
Associate Professor, Department
of Zoology, Wildlife Limnology
and Toxicology Research
Laboratory, Government Meera
Girls College (MLSU), Udaipur,
Rajasthan, India
Dengue and natural remedies for its prevention
and control: A review
Narayan Lal Choudhary, Pushkar Kumawat, Pritesh Patel and Nadim
Chishty
DOI: https://doi.org/10.22271/23487941.2022.v9.i6b.646
Abstract
Dengue virus is the most common mosquito borne viral infection and is caused by four different
serotypes of dengue virus, named DENV-1, DENV-2, DENV-3 and DENV-4, which belongs to
Flaviviridae family and Flavivirus genus. It is transmitted by the Aedes mosquito from one infected
person to another healthy person. A frontal headache, retro-orbital pain, body aches, rashes, nausea,
vomiting, weakness and a high body temperature are the main symptoms of dengue infection. Dengue
haemorrhagic fever and dengue shock syndrome can result in death in severe cases if proper treatment is
not given. Several medical technologies, such as monoclonal antibodies, tetravalent subunits, inactivated
and live attenuated vaccines have been adopted globally, but developing and under developed countries
cannot afford them due to high costs. Various developing countries use herbal and natural remedies to
prevent and control dengue. In this review, we are discussing about various plant species that have
antiviral, ovicidal, larvicidal and mosquito repellent properties as well as compound that can be used to
treat dengue fever.
Following species of plants Momordica charantia, Alternanthera philoxeroides, Andrographis
paniculata, Cladosiphon okamuranus, Carica papaya, Momordica charantia, Andropogon citratum,
Curcuma longa, Piper longum, Piper ribesoides, Piper sarmentosum, Eupatorium perfoliatum,
Kaempferia parviflora, Solanum villosum, Azadirachta indica, Pongamia glabra, Eupatorium odoratum,
Catharanthus roseus, Nyctanthes arbor-tristis, Acalypha alnifolia, Delonix elata, Ocimum sanctum,
Tinospora rumphii, Citrus grandis, Jatropha curcas, Ageratum houstonianum, Albizia lebbeck,
Aristolochia bracteata, Houttuynia cordata, Hippophae rhamnoides, Kaempferia parvifora, Leucaena
leucocephala, Mimosa scabrella, Piper sarmentosum, Psidium guajava, Rhizophora apiculata,
Boesenbergia rotunda and Quercus lusitanica are widely used for treatment and control of dengue. Plant
products and herbal remedies provided alternative of medicine for cure and recovery of various diseases
including dengue fever.
Keywords: Dengue, Aedes, natural remedies, plant, vaccine, symptoms
Introduction
Dengue fever is most common mosquito-borne viral infection and has rapidly become a major
global health problem
[1]
. Dengue fever is a viral disease that has highly influenced human
health and caused adverse impacts on tropical and subtropical regions
[2]
. At present, four
different types of dengue serotypes have been identified that are DENV-1, DENV-2, DENV-3
and DENV-4 and which belongs to the Flaviviridae family and Flavivirus genus
[2, 3, 4]
. It is
spreaded by Aedes mosquitoes, primarily who breeds in urban habitats
[2, 3, 4, 5]
. According to
WHO, dengue is widespread in over 100 nations including the Asia, Americas, Africa, Pacific
and Caribbean regions. Dengue cases have sharply risen in worldwide and currently reached
pandemic levels
[6]
. Approximately 2.5 billion peoples are supposed to be at risk of dengue
infection and an estimated 50 million cases are reported annually
[6]
. Dengue disease is not
only a burden on health care but also has a negative influence on the economy due to illness,
premature death and rising healthcare expenses
[7]
. At present dengue fever occurs in both
epidemic and scattered forms
[2, 8]
. Most dengue infections cause nonspecific symptoms such
as body aches, nausea, vomiting, weakness, rash, retro-orbital pain and frontal headache
[9, 10]
.
Several medical technologies have been used to combat DENV, including monoclonal