To cite this paper: ElBakrey RM, Helal SS, ElKholy AA, and Eid AAM (2024). Landmarks in Quail Coccidiosis Research with Special Scrutiny to the Available Egyptian Literature: A Review. J. World Poult. Res., 14(2): 181-195. DOI: https://dx.doi.org/10.36380/jwpr.2024.19 181 JWPR Journal of World’ s Poultry Research 2024, Scienceline Publication J. World Poult. Res. 14(2): 181-195, 2024 Review Paper DOI: https://dx.doi.org/10.36380/jwpr.2024.19 PII: S2322455X2400019-14 Landmarks in Quail Coccidiosis Research with Special Scrutiny to the Available Egyptian Literature: A Review Reham M. El Bakrey , Sarah S. Helal , Ahmed A. El Kholy , and Amal A. M. Eid* Department of Avian and Rabbit Medicine, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Sharkia 44511, Egypt *Corresponding author’s E-mail: amalaeidvet@gmail.com Received: March 23, 2024, Revised: April 25, 2024, Accepted: May 26, 2024, Published: June 30, 2024 ABSTRACT Quails are an important alternative to chicken production for protein sources, offering many advantages over other poultry species. However, raising quail faces certain challenges, such as a shortage of specified hatcheries and the lack of local markets for quail eggs and meat, particularly in Egypt. In addition, there is less interest in quail’s medication and vaccine production. A significant disease affecting t he health and productivity of quails is coccidiosis, which is associated with poor feed conversion ratio, lower growth performance, heightened mortality, and high cost of vaccination and treatment. Attention to quail coccidiosis and its clinical forms, diagnosis, morphological characterization, control, and prevention is very critical for improving quail meat and egg production. This review compiles scientific data on quail coccidiosis, with a focus on literature from Egypt, for classification, data analysis, and processing. Keywords: Anticoccidial, Coccidiosis, Eimeria, Egyptian, Morphology characterization, Quail INTRODUCTION Coccidiosis is a protozoan disease caused by coccidia of the genus Eimeria (Kemp et al., 2013). Over 1800 different species of Eimeria invade and infect the digestive tracts of mammals and birds, either wild or domesticated (Haug et al., 2008). When Eimeria species target the intestinal tract, they induce a potent inflammatory response and tissue damage, with increased susceptibility to other disease agents, and mortalities in severe cases (Duszynski, 2011). Eimeria species have a complex life cycle that involves both intra- and extracellular stages and is completed in a single host due to their high host specificity, in particular Eimeria (E.) tsunodai, E. uzura, and E. bateri in quails (Lu et al., 2021). Each Eimeria species replicates to form oocysts in the intestine of the host, which are then released into the environment via feces. Birds ingest sporulated oocysts, which are then transported to the intestine to begin their life cycle (Chapman, 2014). Several studies have focused on the pathogenesis, pathogenicity, control, and prevention of coccidia in domesticated poultry due to the significant economic losses associated with both subclinical and clinical infections (Nawarathne et al., 2021). Quails, in particular, are considered a viable alternative in poultry production because of their high potential for meat and egg production. Quail farming is a rapidly developing sector worldwide (Lukanov, 2019). In Egypt, with a growing population and an increasing demand for animal proteins, quail breeding has gained attention as a means to boost and expand the production of meat protein (Arafat and Abbas, 2018; Ramadan et al., 2021). Quails are susceptible to several diseases, with coccidiosis being the most significant. This dangerous parasitic disease poses a major threat to the quail industry (Umar et al., 2014). On the other hand, there is limited information available about quail coccidiosis, including its distinct phenotypic and genetic characteristics (Arafat and Abbas, 2018). This article could provide the existing studies on coccidiosis in quails, emphasizing the disease's distinguishing characteristics and key features. The review focuses particularly on data and results from available literature, with special attention to studies conducted in Egypt. MATERIALS AND METHODS In the current review, the available literature of previous international and Egyptian studies (Scopus, PubMed, and Google Scholar) concerned with quail ISSN: 2322-455X License: CC BY 4.0