Shrestha et al. World Journal of Pharmacy and Pharmaceutical Sciences www.wjpps.com │ Vol 13, Issue 8, 2024. │ ISO 9001:2015 Certified Journal │ 734 PRESCRIBING PATTERN OF PSYCHOTROPIC DRUG AMONG SCHIZOPHRENIA AND RELATED PSYCHOTIC DISORDER PATIENTS Sabin Shrestha 1 *, Nabina Basaula* 1 , Rahi Bikram Thapa 2 , Pharsuram Adhikari 1 and Nayem Uddin Prince 3 1 Department of Pharmacy, Manmohan Memorial Institute of Health Science, Soalteemode, Kathmandu, Nepal. 2 Department of Pharmacy, Purbanchal University School of Health Science, Gothgaun, Morang, Nepal. 3 Department of Information Technology, Washington University of Schools of Technology, USA. ABSTRACT Background: Psychotic disorders, like schizophrenia, are a global public health concern requiring efficient management and accessible, affordable treatment options to minimize severe consequences. Objective: To assess the prescription pattern of psychotropic drugs given to patients with schizophrenia and related psychotic disorders. Method: A cross-sectional observational study was conducted at the Mental Hospital, targeting patients diagnosed with schizophrenia and related psychotic disorders. A total of 119 samples were collected over three months. Data was extracted from patient cardex, case sheets, discharge summaries, and interviews. The results were analyzed using descriptive methods and expressed as numbers and percentages. Results: The study analyzed 119 prescriptions for schizophrenia and related psychotic disorders, revealing that the most common age group affected was 30-39 years, with a higher prevalence of male patients. 18.5% of patients had a family history of psychotic disorders, and 10.1% had a history of head injuries. The majority of patients were diagnosed with unspecified non-organic psychosis (66.4%), followed by schizophrenia (25.2%). Atypical antipsychotics were used in 98.3% of patients, with trifluoperazine being the most prescribed WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES SJIF Impact Factor 8.025 Volume 13, Issue 8, 734-745 Research Article ISSN 2278 – 4357 *Corresponding Author Sabin Shrestha and Nabina Basaula Department of Pharmacy, Manmohan Memorial Institute of Health Science, Soalteemode, Kathmandu, Nepal. Article Received on 30 May 2024, Revised on 20 June 2024, Accepted on 10 July 2024 DOI: 10.20959/wjpps20248-27866