Journal Pre-proof Investigation of Temporal Illicit Drugs, Alcohol and Tobacco Trends in Istanbul City: Wastewater Analysis of 14 Treatment Plants F Asicioglu , M Kuloglu Genc , T Tekin Bulbul , M Yayla , SZ Simsek , C Adioren , S Mercan PII: S0043-1354(20)31262-8 DOI: https://doi.org/10.1016/j.watres.2020.116729 Reference: WR 116729 To appear in: Water Research Received date: 18 September 2020 Revised date: 2 December 2020 Accepted date: 5 December 2020 Please cite this article as: F Asicioglu , M Kuloglu Genc , T Tekin Bulbul , M Yayla , SZ Simsek , C Adioren , S Mercan , Investigation of Temporal Illicit Drugs, Alcohol and Tobacco Trends in Istanbul City: Wastewater Analysis of 14 Treatment Plants, Water Research (2020), doi: https://doi.org/10.1016/j.watres.2020.116729 This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2020 Published by Elsevier Ltd.