1 Accepted APJCP-2103-6625 (R1) Title: Caspase dependent apoptosis induced by Simarouba glauca on lung adenocarcinoma cell lines Biba Vikas, MSc, PhD 1 , Kunjiraman Sujathan, PhD 2 , Suja Somasekharan Nair Rajam, PhD 1 , Sukumaran Anil, MDS, PhD, FDS RCS 3,4 1. Jawaharlal Nehru Tropical Botanic Garden and Research, Trivandrum, Kerala, India 2. Regional Cancer Centre, Trivandrum, Kerala, India. 3. Department of Dentistry, Oral Health Institute, Hamad Medical corporation, Doha, Qatar. 4. Professor, College of Dental Medicine, Qatar University, Doha, Qatar. Running title: Apoptosis induced by Simarouba glauca on lung adenocarcinoma Corresponding Author: Dr. Biba Vikas. MSc, PhD Jawaharlal Nehru Tropical Botanic Garden and Research, Palode, Kerala 695562 INDIA E-mail: bibavikas@gmail.com Statement conflict of Interest: None