Journal of Cardiovascular Disease Research ISSN: 0975-3583,0976-2833 VOL12, ISSUE 06, 2021 1675 ORIGINAL RESEARCH Perioperative outcome of Coronary Artery Bypass Grafting in patients with or without Percutaneous Coronary Intervention 1 Dr. Amaresh Rao Malempati, 2 Dr. Palanki Surya Satya Gopal, 3 Dr. Kalyan Babu B, 4 Dr. Madhusudan Lal Kummari, 5 Dr. Kaladhar Bomma 1 Additional Professor, 2,4,5 Associate Professor, 3 Resident, Department of Cardiothoracic Surgery, Nizam’s Institute of Medical Sciences, Punjagutta, Hyderabad, Telangana, India Correspondence: Dr. Palanki Surya Satya Gopal Associate Professor, Department of Cardiothoracic Surgery, Nizam’s Institute of Medical Sciences, Punjagutta, Hyderabad, Telangana, India Email: gopal.palanki@gmail.com Abstract Background: Coronary artery disease (CAD) is a major cause of death in developed countries, and this disease is diagnosed in an increasing number of adults nowadays, particularly among young patients Aims: The study aims to compare the differences in the early outcomes of patients undergoing Coronary Artery Bypass Grafting (CABG) who had prior Percutaneous Transluminal Coronary Angioplasty versus those who have not. Materials and methods: Perioperative outcome of CABG (Coronary Artery Bypass Grafting) in patients with or without primary PCI (Percutaneous Coronary Intervention) single institute a retrospective and prospective study of 100 cases during the period of 2016 to 2020. Results: The EuroScore in PCI group is higher than the Non PCI group undergoing CABG and difference was found to be statistical significance. The need for post surgery IABP was higher in Non PCI group. ICU stay the patient in Non PCI had lower ICU stay then PCI group which is having statistical significance. The mortality was higher in Non PCI group compare to PCI group but not statistical significance. Conclusions: In conclusion, CABG remains the best revascularization strategy in MVD( Multi vessel Disease), conferring reduced mortality and repeat revascularization risk. The absolute risk increases in stroke associated with CABG does not outweigh the benefit in the long-term survival achievable with this technique of revascularization. Keywords: Coronary Artery Bypass Grafting (CABG), Percutaneous Coronary Interventions, revascularization Introduction Coronary Artery Bypass Grafting (CABG) and Percutaneous Coronary Interventions (PCI) are established modes of treatment of Symptomatic Coronary Artery Disease. CABG remains the gold standard in the treatment of significant triple vessel disease. Where asPCIs have gained increasing popularity in recent times because of the relatively lesser invasiveness and early recovery especially when 2 or less vessels are involved. However, a considerable number of patients after prior PCI develop progressive disease and present to CABG surgery. There are studies which suggest increased incidence of adverse outcomes in CABG in patients who have undergone prior PCI 1-3 but the relationship is not fully established. The cause for this is not delimited. Although the EUROSCORE(European system for cardiac