Accepted Manuscript Design, Synthesis and Antibacterial Activities of Thiouracil Derivatives Con- taining Acyl Thiourea as SecA inhibitors Penglei Cui, Xiaoliu Li, Mengyuan Zhu, Binghe Wang, Jing Liu, Hua Chen PII: S0960-894X(16)31212-4 DOI: http://dx.doi.org/10.1016/j.bmcl.2016.11.060 Reference: BMCL 24455 To appear in: Bioorganic & Medicinal Chemistry Letters Received Date: 20 July 2016 Revised Date: 11 November 2016 Accepted Date: 22 November 2016 Please cite this article as: Cui, P., Li, X., Zhu, M., Wang, B., Liu, J., Chen, H., Design, Synthesis and Antibacterial Activities of Thiouracil Derivatives Containing Acyl Thiourea as SecA inhibitors, Bioorganic & Medicinal Chemistry Letters (2016), doi: http://dx.doi.org/10.1016/j.bmcl.2016.11.060 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.