CLINICAL NOTE
A Rare Prevertebral Ordinary Lipoma Presenting
as Obstructive Sleep Apnea
Computed Tomographic and Magnetic Resonance Imaging Findings
Jean Anderson Eloy, MD; Eduarda Carneiro, MD; Prasanna Vibhute, MD;
Eric M. Genden, MD; Joshua B. Bederson, MD; Peter M. Som, MD
L
ipomas are among the most common benign tumors of mesenchymal origin, having
been described in virtually every area of the body.
1-7
We describe a 65-year-old woman
presenting with snoring and obstructive sleep apnea (OSA) secondary to a prevertebral
cervical lipoma that extended into the right parapharyngeal space and into the spinal
canal through the right C2-C3 neural foramen. Only 1 prior similar case has been reported in the
English literature.
8
Complete surgical removal of the lesion was performed through a lateral cer-
vical approach.
REPORT OF A CASE
A 65-year-old woman with no significant
medical history presented to our Head and
Neck Cancer Center with worsening snor-
ing and OSA. Results of the physical exami-
nation showed right posterior pharyngeal
wall fullness with diminution of the oro-
pharyngeal airway. Computed tomo-
graphic (CT) imaging (Figure 1) showed
a fatty attenuation consisting of a lobu-
lated prevertebral mass that displaced the
right posterior oropharyngeal wall for-
ward, minimally displaced the right ca-
rotid sheath laterally, and extended into the
right C2-C3 neural foramen. Magnetic reso-
nance (MR) imaging (Figure 2) showed
the mass to have signal intensities consis-
tent with fat. The patient underwent surgi-
cal excision of the lesion via a lateral trans-
cervical approach. Her postoperative course
was unremarkable, and she was dis-
charged on the second postoperative day in
stable condition. At present, the patient is
healthy with complete resolution of her
snoring and OSA. Findings from pathologi-
cal examination of the excised specimen
showed an ordinary lipoma.
COMMENT
Lipomas are generally encapsulated sub-
cutaneous or submucosal masses that pri-
marily arise in the superficial soft tissues.
As such, they are referred to as ordinary
lipomas.
1
There is also an infiltrating or
intramuscular type of lipoma that infil-
trates surrounding skeletal muscles and tis-
sues, has an incomplete capsule, and has
a high rate of recurrence after resection.
2
Only 13% to 15% of lipomas present in the
head and neck, with the posterior tri-
angle of the neck being the most com-
mon affected site. However, the anterior
neck, infratemporal fossa, oral cavity, phar-
ynx, and larynx also may be involved.
3
Li-
pomas posterior to the pharynx are un-
common, with only about 30 cases
described since the late 1800s.
3
Preverte-
bral lipomas are rare, and owing to their
clinically inaccessible location, CT and/or
MR imaging are important tools for their
pretreatment diagnosis. However, be-
cause liposarcomas can occasionally ap-
pear similar to lipomas on CT and MR
imaging, histological confirmation is es-
sential for a definitive diagnosis.
The 3 spaces behind the pharynx in
which such a lipoma might arise include
the retropharyngeal space, the danger space,
and the prevertebral space. Most reported
cases of lipomas in this area have been de-
scribed as arising in the retropharyngeal
Author Affiliations: Departments of Otolaryngology–Head and Neck Surgery
(Drs Eloy, Genden, and Som), Radiology (Drs Vibhute and Som), and
Neurosurgery (Dr Bederson), Mount Sinai School of Medicine, and Head and Neck
Cancer Center, Mount Sinai Medical Center (Drs Genden and Som), New York,
New York; and Department of Neuroradiology, Sa˜o Joao Hospital, Porto, Portugal
(Dr Carneiro).
(REPRINTED) ARCH OTOLARYNGOL HEAD NECK SURG/ VOL 134 (NO. 9), SEP 2008 WWW.ARCHOTO.COM
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©2008 American Medical Association. All rights reserved.