Biomedical & Pharmacology Journal, December 2021. Vol. 14(4), p. 2285-2294 Published by Oriental Scientific Publishing Company © 2021 This is an Open Access article licensed under a Creative Commons license: Attribution 4.0 International (CC-BY). Assessment of Psychology, Behaviour and Self-Medication Potential Among Indian People During COVID-19 Pandemic Atreyee Sarkar* and Jaya Kumar Rajamani Gitam University, NH 207, Nagadenahalli, Doddaballapura, Karnataka 561203, India. *Corresponding Author E-mail: atrkar87@gmail.com https://dx.doi.org/10.13005/bpj/2329 (Received: 23 January 2021; accepted: 18 November 2021) This research work was done during the Indian festive season of 2020 to assess the attitude, mentality and psychological pattern of Indians. Also, the effect of yoga and meditation in combating the Covid-19 pandemic related stress was analyzed in the present research work. As Paracetamol and Diclofenac are OTC medications which are widely available without doctor’s prescription, the potential of self-medication for these drugs amidst the pandemic need to be studied, this study further attempted to analyze the rate and extent of self-medication of these drugs among Indians. An e-questionnaire survey bearing questions on pandemic-related mental stress, sleep duration, yoga, meditation practice, and extent of self-medication in combating the pandemic was floated to the residents of Bengaluru to collect their response. The collected data were analyzed using Statistical Package for the Social Sciences software version 17. A mixed response regarding their stress, anxiety, and fear expressed on a higher scale was the same before or during Covid could be perceived. The sleep pattern before and during CoVid had no significant variation (p>0.05) and appeared the same. All the respondents agreed that they spend considerable time with electronic gadgets during the Covid lockdown period. Most of the respondents (60%) practice yoga and meditation occasionally or daily. The high rate of self-medication with Paracetamol and Diclofenac drugs among Indian people in the current pandemic situation shows they are OTC and readily available. The self-medication practice is of real concern as it may cause a long-term impact on the consumers. Keywords: COVID-19; Diclofenac; Meditation; Psychology; Paracetamol; Self-Medication; Yoga. In December 2019, few cases of an unidentified pneumonia came up in Huanan Seafood Wholesale Market which is a wet market in Wuhan, China. The disease characteristics were similar to that reported by virus flu. This causative agent was later identified as SARS-Cov-2 virus which caused symptoms like fever, cough, diarrhoea, fatigue and vomiting. Some severe cases caused acute respiratory distress, heart injury and secondary infections. 1,2 The World Health Organization declared it as a pandemic on March 11, 2020. The virus inflicts fear of getting sick, dying due to infection, stigma and helplessness among common people. 3 Quarantine is a traditional method of containing the spread of epidemic diseases. 4 Mass fear of Covid 19 is called as “coronaphobia”. Nationwide lockdowns are being reported to cause mass hysteria, anxiety, depression, rise in substance dependence, irritability, confusion, anger, insomnia, denial, despair, fear of getting the disease, post-traumatic stress disorder and even suicidal thoughts. 5 Medicating someone in order to alleviate or prevent an illness without medical supervision