www.iajpr.com Page1565 Indo American Journal of Pharmaceutical Research, 2021 ISSN NO: 2231-6876 INVITRODRUG RELEASE STUDIES AND EVALUATION FOR CO-CRYSTALS OF ATAZANAVIR Syeda Asra Banu *1 , Dr. Damineni Saritha 1 , Dr. Anupama Koneru 3 1 Department of Pharmaceutics, Sultan-Ul-Uloom College of Pharmacy, Hyderabad, Telangana, India. 2 Sultan-Ul-Uloom College of Pharmacy, Hyderabad, Telangana, India. Corresponding author Syeda Asra Banu Assistant Professor, Department of Pharmaceutics, Sultan-Ul-Uloom College of Pharmacy, Hyderabad, Telangana, India. Copy right © 2021 This is an Open Access article distributed under the terms of the Indo American journal of Pharmaceutical Research, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ARTICLE INFO ABSTRACT Article history Received 17/12/2020 Available online 01/03/2021 Keywords Atazanavir, Co-Crystals And Drug Release. The present study is of formulation and evaluation of Atazanavir co-crystals to improve drug oral bioavailability. Atazanavir co crystals were prepared by sovent evaporation technique using Oxalic acid, succinic acid, saccharin, were as co crystal formers, various formulations were prepared these polymers. The Atazanavir co-crystals were characterized with respect to IR, DSC, XRD, angle of repose, bulk density, tapped density, Carr’s index, Hausner’s ratio, and stability studies and all the results indicated that the co-crystals were having good flow nature. Conclusion: By the in vitro dissolution studies it was concluded that the formulation prepared with oxalic acid in the concentration of 200mg (F4) was showing better result 98.97% drug release. Please cite this article in press as Syeda Asra Banu et al. Invitrodrug Release Studies and Evaluation for Co-Crystals of Atazanavir. Indo American Journal of Pharmaceutical Research.2021:11(02).