Enfermedades infecciosas y seguridad mundial: Análisis de las estrategias mundiales de control y vacunación Salud, Ciencia y Tecnología. 2024; 4:.582 doi: 10.56294/saludcyt2024.582 REVIEW Infectious diseases and global security: Analysis of global control and vaccination strategies Beata Strzelecka 1 , Ledi Necaj 2 , Katarzyna Wisniewska 3 , Samuel Stroz 4 , Mateusz Bartoszewicz 5  ABSTRACT Introduction: given the recent experience with the COVID-19 vaccine campaign, an optimal global policy to control future pandemics and ensure infectious security globally is highly relevant. Objective: the study aims to determine the optimal vaccination strategy to reduce COVID-19 morbidity and mortality during a pandemic. Method: a systematic search of studies on infectious disease control and vaccination strategies for the period 2000-2023 in PubMed, Scopus, Web of Science and Google Scholar databases using keywords was conducted for the review. Relevant publications, data extraction and systematisation were selected. Results: the findings of the analysis highlight the importance of integrated interventions in global vaccination strategies, including health systems strengthening, innovative technologies for outbreak detection and international collaboration. Vaccination, as an effective preventive measure, significantly reduces the spread of infectious diseases. Vaccination with different types of vaccines has been shown to improve immune response compared to the use of the same type of vaccine. This approach, where the first and second vaccine doses are different, may increase the effectiveness of the immune response. Conclusions: studies confirm that vaccination reduces the number of cases and deaths, reducing the economic burden. A variety of vaccines, including mRNA, vector, and inactivated vaccines, provide high efficacy in preventing COVID-19 infection and mortality, especially when a heterologous vaccination regimen is used. This review identifies the most effective infectious disease control strategies for the development of global health recommendations. Keywords: Coronavirus Infection; Epidemiology; International Cooperation; Pandemic; Prevention and Control. RESUMEN Introducción: dada la reciente experiencia con la campaña de vacunación contra el COVID-19, es muy pertinente contar con una política mundial óptima para controlar futuras pandemias y garantizar la seguridad infecciosa en todo el mundo. Objetivo: el estudio pretende determinar la estrategia de vacunación óptima para reducir la morbilidad y mortalidad por COVID-19 durante una pandemia. © 2024; Los autores. Este es un artículo en acceso abierto, distribuido bajo los términos de una licencia Creative Commons (https:// creativecommons.org/licenses/by/4.0) que permite el uso, distribución y reproducción en cualquier medio siempre que la obra original sea correctamente citada 1 Faculty of Health Sciences, Radom Higher School, Radom, Poland. 2 Department of Clinical Subjects and General Nursing, Internal Disease Nursing, Pediatrics, University of Medicine, Tirana, Tirana, Albania. 3 Department of Clinical Immunology, Medical University of Bialystok, Bialystok, Poland. 4 Department of Anaesthesiology and Intensive Care, Medical University of Bialystok, Bialystok, Poland. Cite as: Strzelecka B, Necaj L, Wisniewska K, Stroz S, Bartoszewicz M. Infectious diseases and global security: Analysis of global control and vaccination strategies. Salud, Ciencia y Tecnología. 2024; 4:.582. https://doi.org/10.56294/saludcyt2024.582 Submitted: 28-08-2023 Revised: 03-02-2024 Accepted: 18-09-2024 Published: 19-09-2024 Editor: Dr. William Castillo-González Corresponding author: Beata Strzelecka 