Endocrinol Nutr. 2012;59(2):105---108 ENDOCRINOLOGÍA Y NUTRICIÓN www.elsevier.es/endo ORIGINAL ARTICLE Thyroid carcinoma in children and adolescents: A retrospective review Filipa Neiva ∗ , Joana Mesquita, Susana Paco Lima, Maria João Matos, Carla Costa, Cintia Castro-Correia, Manuel Fontoura, Sofia Martins Unidade de Endocrinologia Pediátrica, Servic ¸o Pediatria, Hospital São João, Porto, Portugal Received 10 August 2011; accepted 2 November 2011 Available online 3 January 2012 KEYWORDS Retrospective study; Thyroid carcinoma Abstract Objective: To describe clinical presentation, preoperative study, intervention, histology, surgi- cal complications and follow-up characteristics, and survival in patients with thyroid carcinoma (TC) with less than 18 years at presentation. Material and methods: retrospective analysis of clinical data of all children and adolescents followed in S. João Hospital from January 1, 2000 to March 31, 2010 with histologic diagnosis of TC. Results: Twenty-three patients were identified, 19 girls, and 4 boys. Median age at presentation was 17.0 years. Annual incidence was 2.3 cases/year. The main presenting symptom was a solitary thyroid nodule (60.8%). Three (13%) patients had risk factors for TC, 2 of the 3 had previous cervical irradiation. The other was a smoker. Total thyroidectomy was performed in 16 (69.6%), and 10 patients underwent a second surgical procedure. Four (17.4%) patients had postoperative complications. Histologic examination revealed differentiated TC in all, papillary thyroid carcinoma (PTC) in 86.9%, follicular carcinoma in the remaining. All patients received thyroxine suppressive therapy and 20 underwent therapeutic radioactive iodine ( 131 I). During follow-up (7.1 years), 7 out of the 23 patients presented new metastases and needed new treatment. All patients are currently alive. Conclusions: TC is a reality in pediatric population, thyroid routine examination should take part in all clinical examination in children and adolescents. © 2011 SEEN. Published by Elsevier España, S.L. All rights reserved. PALABRAS CLAVE Estudio retrospectivo; Cáncer de tiroides Carcinoma tiroideo en ni˜ nos y adolescentes: estudio retrospectivo Resumen Objetivo: Describir la presentación clínica, el estudio preoperatorio, la intervención quirúrgica y complicaciones, así como la histología, el seguimiento y la supervivencia de pacientes con carcinoma tiroideo (CT) cuya edad es inferior a los 18 a˜ nos en el momento de la presentación. ∗ Corresponding author. E-mail address: afneiva@gmail.com (F. Neiva). 1575-0922/$ – see front matter © 2011 SEEN. Published by Elsevier España, S.L. All rights reserved. doi:10.1016/j.endonu.2011.11.003 Document downloaded from http://zl.elsevier.es, day 12/08/2017. This copy is for personal use. Any transmission of this document by any media or format is strictly prohibited.