_____________________________________________________________________________________________________ ++ Consultant Breast Surgeon; # Consultant Radiologist; *Corresponding author: E-mail: Rufina.soomro@hotmail.com; J. Adv. Med. Med. Res., vol. 36, no. 4, pp. 21-28, 2024 Journal of Advances in Medicine and Medical Research Volume 36, Issue 4, Page 21-28, 2024; Article no.JAMMR.113883 ISSN: 2456-8899, NLM ID: 101711724 (Past name: British Journal of Medicine and Medical Research, Past ISSN: 2231-0614, NLM ID: 101570965) Implementation of Targeted Axillary Node Assessment Following Neoadjuvant Therapy for Node-positive Breast Cancer Patients Improves Axillary Disease Detection Rufina Soomro a++* , Afsheen Javaid Khokher a++ and Sadaf Nasir a# a Liaquat National Hospital and Medical College, Pakistan. Authors’ contributions This work was carried out in collaboration among all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JAMMR/2024/v36i45396 Open Peer Review History: This journal follows the Advanced Open Peer Review policy. Identity of the Reviewers, Editor(s) and additional Reviewers, peer review comments, different versions of the manuscript, comments of the editors, etc are available here: https://www.sdiarticle5.com/review-history/113883 Received: 01/01/2024 Accepted: 05/03/2024 Published: 08/03/2024 ABSTRACT Background: Assessing the targeted node, a biopsy-proven metastatic node marked with a metallic clip before neoadjuvant chemotherapy along with sentinel node dissection improves the evaluation of pathological response in the axillary nodal basin after systemic treatment as compared to sentinel node dissection with dual tracer alone. Objectives: The objective was to investigate the rate of the clipped node being a sentinel node and the sensitivity of targeted node dissection in detecting residual disease. Original Research Article