Research Article
Mindfulness for Motor and Nonmotor Dysfunctions in
Parkinson’s Disease
Nadeeka N. W. Dissanayaka,
1,2,3
Farah Idu Jion,
1,2
Nancy A. Pachana,
2
John D. O’Sullivan,
3,4
Rodney Marsh,
1,5
Gerard J. Byrne,
1,4,5
and Paul Harnett
2
1
UQ Centre for Clinical Research, e University of Queensland, Brisbane, QLD 4029, Australia
2
School of Psychology, e University of Queensland, Brisbane, QLD 4067, Australia
3
Neurology Research Centre, Royal Brisbane & Women’s Hospital, Brisbane, QLD 4029, Australia
4
School of Medicine, e University of Queensland, Royal Brisbane & Women’s Hospital, Brisbane, QLD 4029, Australia
5
Mental Health Service, Royal Brisbane & Women’s Hospital, Brisbane, QLD 4029, Australia
Correspondence should be addressed to Nadeeka N. W. Dissanayaka; n.dissanayaka@uq.edu.au
Received 18 November 2015; Revised 5 March 2016; Accepted 28 March 2016
Academic Editor: Ivan Bodis-Wollner
Copyright © 2016 Nadeeka N. W. Dissanayaka et al. is is an open access article distributed under the Creative Commons
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is
properly cited.
Background. Motor and nonmotor symptoms negatively influence Parkinson’s disease (PD) patients’ quality of life. Mindfulness
interventions have been a recent focus in PD. e present study explores effectiveness of a manualized group mindfulness
intervention tailored for PD in improving both motor and neuropsychiatric deficits in PD. Methods. Fourteen PD patients
completed an 8-week mindfulness intervention that included 6 sessions. e Five Facet Mindfulness Questionnaire (FFMQ),
Geriatric Anxiety Inventory, Hamilton Depression Rating Scale, PD Cognitive Rating Scale, Unified PD Rating Scale, PD Quality
of Life Questionnaire, and Outcome Questionnaire (OQ-45) were administered before and aſter the intervention. Participants
also completed the FFMQ-15 at each session. Gains at postassessment and at 6-month follow-up were compared to baseline using
paired -tests and Wilcoxon nonparametric tests. Results. A significant increase in FFMQ-Observe subscale, a reduction in anxiety,
depression, and OQ-45 symptom distress, an increase in PDCRS-Subcortical scores, and an improvement in postural instability,
gait, and rigidity motor symptoms were observed at postassessment. Gains for the PDCRS were sustained at follow-up. Conclusion.
e mindfulness intervention tailored for PD is associated with reduced anxiety and depression and improved cognitive and motor
functioning. A randomised controlled trial using a large sample of PD patients is warranted.
1. Introduction
Parkinson’s disease (PD) is a chronic, progressive, incurable,
complex, and disabling age-related disease. Classically, PD is
characterised by abnormalities in movement; however, non-
motor symptoms including depression, anxiety, and cognitive
decline are frequently experienced in PD [1–3]. Both motor
and nonmotor symptoms negatively impact PD patients’
quality of life. Over 50% of PD patients experience anxiety
and depressive disorders [4]. e majority of PD patients
develop mild cognitive impairment that may progress to
dementia at advanced PD. e prevalence of dementia in
advanced stage PD exceeds 80% [5]. At present, there are
no effective therapies to treat anxiety or cognitive deficits
in PD; very few randomised controlled psychotherapy trials
for depression in PD have been attempted [6–8]. While
Cognitive Behaviour erapy (CBT) has been a popular
psychotherapy method trialled in PD [6], there has been
relatively little attention directed to mindfulness interven-
tions in PD [9]. e present study explores the benefits of a
manualized and tailored mindfulness group intervention to
reduce anxiety and depressive symptoms in PD. e study
also investigates the impact of the intervention on cognitive
and motor symptoms in PD.
“Mindfulness” refers to the process of bringing awareness
to moment-by-moment experience in a compassionate and
nonjudgmental manner [10]. It can be further defined as
a process of self-regulation of attention through increased
Hindawi Publishing Corporation
Parkinson’s Disease
Volume 2016, Article ID 7109052, 13 pages
http://dx.doi.org/10.1155/2016/7109052