_____________________________________________________________________________________________________ *Corresponding author: E-mail: justerm@yahoo.com; Journal of Applied Life Sciences International 11(1): 1-14, 2017; Article no.JALSI.31041 ISSN: 2394-1103 SCIENCEDOMAIN international www.sciencedomain.org Association between Malnutrition and Immunoglobulin G Responses to Crude Asexual P. falciparum schizont Lysates in Children Attending Ishiara Hospital, Embu County, Kenya Mungiria Juster 1* , Gicheru Michael 1 , David Kavili 1 and Mburu David 2 1 Department of Zoological Sciences, Kenyatta University, Nairobi, Kenya. 2 Department of Biochemistry and Biotechnology, Kenyatta University, Nairobi, Kenya. Authors’ contributions This work was carried out in collaboration between all authors. Authors MJ, GM, DK and MD designed the study, performed the statistical analysis, wrote the protocol and wrote the first draft of the manuscript. Authors MJ, DK and GM managed the analyses of the study. Authors MJ and MD managed the literature searches. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JALSI/2017/31041 Editor(s): (1) Rohit Saluja, Department of Dermatology and Allergy, Charité – Universitätsmedizin Berlin, Germany. Reviewers: (1) Jaffu Othniel Chilongola, Kilimanjaro Christian Medical University College, Tumaini University, Tanzania. (2) M. C. O. Ezeibe, Michael Okpara University of Agriculture, Umudike, Nigeria. (3) Abdullahi M. Nuhu, Kaduna polytechnic, Kaduna, Nigeria. Complete Peer review History: http://www.sciencedomain.org/review-history/18491 Received 16 th December 2016 Accepted 31 st March 2017 Published 4 th April 2017 ABSTRACT Aim: The aim of this study was to determine levels of Plasmodium falciparum parasitaemia in children and relationship between IgG responses against the parasite and nutritional status of children. Study Design: Cross sectional study of children diagnosed positive for P. faciparum in Ishiara District Hospital, Embu county, Kenya was done between August 2011 and June 2012. Methodology: A total of 380 children, under 5 years who tested positive to P. faciparum infection were used for the study. Children with less than -2 Z score of height-for-age were classified as stunted and those with less than -2 Z score of weight-for-height were classified as wasted. Malnourished children were identified by the criteria of WHO. P. faciparum parasitaemia was determined by microscopy, using Giemsa stained thin and thick blood smears while the parasite`s IgG antibody responses were assessed by the Enzyme linked immune-sorbent assay. Original Research Article